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This review discusses the negative health impacts of testosterone deficiency and the potential adverse effects of 5α-reductase inhibitors, emphasizing the need for patient-physician discussions regarding these treatments.

This study aimed to investigate the effects of antioxidant therapy on skin aging in MetS patients in Latvia but provides no new findings on its effectiveness.

This review discusses the association between alopecia and increased cardiovascular and metabolic risk but reports no definitive clinical results, emphasizing the need for more comprehensive studies on androgenetic alopecia patients.

This meta-analysis reported that photobiomodulation therapy may improve hair density and stimulate hair growth in patients with androgenic alopecia compared to sham treatments, but larger studies are needed to confirm these findings.

This study observed that gender-affirming hormone therapy differentially affects metabolism in mice, with the specific metabolic impacts dependent on the type of hormonal treatment used.

This review discusses the potential benefits of myo-inositol supplementation for insulin resistance-related disorders and diabetic complications, but reports no new clinical results.

This source reports that testosterone therapy may mildly improve sexual desire in women with sexual dysfunction but lacks long-term safety data and cannot be widely recommended, as no formulations are approved for women in most countries.

In this review, researchers provided a comprehensive analysis of anti-androgen therapies for polyendocrine metabolic ovarian syndrome (PMOS/PCOS), examining their efficacy and safety while proposing a phenotype-guided management framework and highlighting research gaps, such as long-term cardiovascular safety and predictive biomarkers.

This review discusses treatments for polycystic ovary syndrome, including lifestyle changes, oral contraceptives, and various medications, and reports no new clinical findings; the authors highlight the potential of statins and inositol for managing symptoms.

This review discusses genetic factors that may influence the effectiveness of metformin in treating polycystic ovary syndrome and emphasizes the need for further research to establish clear benefits.

This case study suggests that palash basti, a form of Ayurvedic treatment, may effectively manage polyendocrine metabolic ovarian syndrome by improving menstrual regularity and hormonal balance, though further studies are needed.

This study found that combined Myo-inositol and D-chiro-inositol therapy improved metabolic and hormonal parameters, including weight, hormone levels, and skin conditions, in women with PCOS after 6 months.

This study discusses the potential of targeting 11β-HSD1 for treating metabolic syndrome and highlights emerging promising data from human trials on selective 11β-HSD1 inhibitors.

Metabolic issues may trigger lymphocytic cicatricial alopecia, and treatments targeting these issues could help.

This review examines the potential of Parquetina nigrescens for managing Polyendocrine Metabolic Ovarian Syndrome, emphasizing its pharmacological activities and highlighting its promise as an affordable complementary therapy.

This review discusses the disruption of hormonal and metabolic rhythms in polycystic ovary syndrome and explores potential drug targets to address its molecular causes, without providing new clinical results.

This study concluded that clomiphene citrate is generally preferred over metformin for inducing ovulation in obese women with PCOS, despite low-quality evidence indicating metformin may be superior to placebo for live births.

This review discusses the pharmacological actions and potential therapeutic benefits of ginsenoside compound K for metabolic disorders, reports no new clinical results, and suggests further research on its bioavailability and toxicity.

In this study, researchers aim to evaluate the effectiveness and safety of combining plum-blossom needle tapping with ginger juice rubbing to prevent hair loss in obese women after metabolic bariatric surgery, through a randomized controlled trial involving 96 participants.

This review synthesizes current evidence on the Warburg effect in anaplastic thyroid carcinoma and discusses potential therapeutic targets, but reports no new clinical results.

This review discusses the pharmacology and potential therapeutic effects of rare ginsenoside compound K on metabolic disorders but presents no new clinical results, highlighting the need for further studies on its bioavailability and toxicity.

This research highlights the crucial roles of B vitamins in metabolism, neurological processes, and DNA functions, and describes emerging therapies that enhance vitamin absorption and therapeutic potential.

This review discusses the creation of transgender-specific guidelines by WPATH and the Endocrine Society, based mostly on clinical experience, and reports no new results.

This chapter reviews the clinical effects of androgens like testosterone and its metabolites on various body systems and life stages, but reports no new results.

This review discusses guidelines for androgen use in women and concludes that more research is needed before recommending testosterone due to insufficient evidence on safety and efficacy.

This review discusses the effects of testosterone therapy for transgender men, noting desired outcomes and potential risks, but reports no new research findings; the authors highlight a lack of high-quality data due to various study limitations.

This article discusses the development of a transdermal testosterone patch for postmenopausal women to deliver physiological testosterone levels but reports no new clinical results, highlighting a need for long-term safety data.

This review discusses the impact of gender affirming hormone therapy on cardiovascular outcomes in transgender individuals and reports no new clinical results; the authors underscore the need for more comprehensive studies.

This study found that menopausal status and hormone therapy significantly affect the histology and gene expression of the introitus, with post-menopausal women showing notable tissue remodeling associated with vaginal atrophy.

This study highlights a close link between metabolic syndrome, characterized by conditions like obesity and hypertension, and various inflammatory skin diseases, suggesting that mitochondrial dysfunction plays a key role in their pathogenesis and could be a target for new therapies.