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The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Zinc is crucial for growth and health in rats.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Biotin supplements may improve hair and nail growth in people with certain deficiencies or conditions, but there's not enough evidence to recommend it for healthy individuals.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Finasteride is a safe, effective treatment for hirsutism with fewer side effects.

Shen-Min, a hair growth supplement, likely caused acute hepatitis in a woman, improving after she stopped taking it.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Metformin and rosiglitazone improve blood vessel function in women with PCOS, with metformin also reducing insulin resistance and testosterone levels.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Minoxidil works in liver and outer hair root sheath for hair growth.

Gefitinib can cause skin problems, diarrhea, and nausea, but rarely causes severe lung disease or hair loss.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Some plants used in traditional medicine may help treat cancer because they contain proteins that can inactivate ribosomes.

Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.

Activating NRF2 might help treat hair disorders by improving antioxidant defenses.

The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

Higher androstenedione levels in women with PCOS are linked to more severe symptoms.

Some skin disorders might be linked to H. pylori infection, but more research is needed to confirm this.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.

New acne treatments show promise as alternatives to traditional therapies.

The document concludes that careful evaluation is needed to diagnose PCOS correctly due to similar symptoms in other conditions, and accurate testosterone level measurement is crucial.

Leucaena leucocephala is nutritious but needs careful processing to remove toxins.

Women with AGA have more androstenedione and dihydrotestosterone, less copper and zinc; copper imbalance affects AGA; treatment improves hormones and minerals.

New pregnane derivatives were more effective than finasteride at inhibiting a key enzyme for male pattern baldness.

Asiasari Radix et Rhizoma is safe and has potential for new drug development due to its therapeutic properties.

Finasteride improved symptoms in a schizophrenia patient.