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Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

Human skin can make serotonin and melatonin.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.

The report recommends personalized treatment for women's sexual dysfunctions and more research on effective therapies.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

The Rotterdam Study aims to understand various diseases in older adults.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

Hair loss needs more research for better treatments.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Pectin biosynthesis is essential for the growth of cotton fibers and Arabidopsis root hairs.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Chemotherapy-induced hair loss significantly affects patients' well-being, and nurses are key in helping them cope, but more research is needed to find effective treatments.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Finasteride safely lowers DHT levels without affecting testosterone.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Tofacitinib helped regrow hair in most adolescents with alopecia areata, but more research is needed.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.