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In this study, severe diffuse hair loss in patients with systemic lupus erythematosus was associated with distinct clinical, dermoscopic, and histopathological features, which improved alongside treatment of the underlying condition.

The document explains various skin conditions in cats and how to diagnose and treat them.

In this study, researchers observed that human sebaceous glands can regenerate in a mouse model using transplanted human skin, potentially offering a tool to study sebaceous gland biology and regeneration.

This study found that a hair-coating polyphenol complex significantly enhanced the mechanical strength, UV protection, and antistatic properties of damaged hair, suggesting potential benefits for hair treatment.

This study observed that a mesotherapy formulation was associated with statistically significant improvements in hair quantity, thickness, and scalp condition among 23 patients with androgenetic alopecia, without noted side effects.

In this study, researchers developed a carboxylated β-cyclodextrin formulation to enhance finasteride's physicochemical properties, achieving an encapsulation efficiency of about 85% and indicating potential for controlled drug release in therapeutic applications. Their findings suggest this inclusion complex could improve delivery of hydrophobic drugs like finasteride.

Scalp tattooing may trigger hair regrowth in alopecia universalis.

This study found that direct immunofluorescence of hair is a simple and non-invasive alternative for monitoring pemphigus vulgaris, matching skin biopsy results in the cases observed.

This review examines the functions of vitamin D and its receptor in skin and explores how these are regulated, reporting no new clinical results.

This review discusses how vitamin D and calcium signaling are essential for wound healing by activating epidermal and hair follicle stem cells, noting that deficiencies may lead to delayed or chronic wounds.

This study found that involucrin likely plays a key role in forming the cornified material of the medulla and inner root sheath of human hair, contributing to its mechanical strength.

This study found that Tcf3 and Lef1 differently regulate cell differentiation in multipotent skin stem cells, with Tcf3 promoting follicle-like features and Lef1, when modified, promoting sebocyte differentiation.

This study found that stabilized beta-catenin is crucial for activating stem cell transition from quiescence to proliferation in hair follicles by influencing gene expression within the stem cell niche.

This review examines how epigenetic dysregulation affects adult stem cell function, noting that impacts range from minor to serious disruptions in tissue homeostasis and potential cancer development.

This review covers recent findings on stem cell plasticity under normal and cancerous conditions but presents no new experimental results, highlighting implications for regenerative medicine and cancer treatments.

This study found that in patients who underwent jejuno-ileal bypass for morbid obesity, dapsone was effective in treating inflammatory skin lesions and joint symptoms when other antibiotics failed.

This study found that mouse FLRG protein, a secreted glycoprotein, is expressed in certain tissues and plays a role distinct from follistatin during wound healing, suggesting different functions in vivo.

In this study, researchers found that changes in the extracellular matrix components, particularly fibronectin, laminin, and type IV collagen, during the rat vibrissa follicle growth cycle, suggest dynamic remodeling related to dermal-epidermal signaling.

This study found that α3β1-integrin is crucial for maintaining normal hair follicle morphology in mice, as its deficiency leads to severe abnormalities despite not affecting interfollicular epidermal differentiation.

This study found significant associations between certain MICA variants and haplotypes with alopecia areata, suggesting MICA as a potential candidate gene linked to the disease's susceptibility and severity.

This review explores research on nanoformulations for enhancing the topical delivery of herbal medicines, noting potential benefits like improved bioavailability and sustained delivery, and emphasizes the need for safety and toxicity guidelines in developing these novel drug delivery systems.

This study found that TSC2-null fibroblast cells from TSC skin hamartomas can induce hair follicle formation and hamartomatous changes in keratinocytes, with active mTOR signaling observable in a mouse xenograft model.

This study found that adapalene-loaded solid lipid microparticles may enhance targeted drug delivery into sebum due to their similarity to sebum components, although both this formulation and a standard cream showed equivalent follicular penetration.

In vitro skin models are improving but still need more innovation to fully replicate human skin.

This study found that electrospun poly(ε-caprolactone)/poly(3-hydroxybutyrate) blend fibers demonstrated nanometric dimensions and promising properties for drug delivery, with curcumin release linked to fiber morphology and processing parameters.

New skin substitutes for treating severe burns and chronic wounds are being developed, but a permanent solution for deep wounds is not yet available commercially.

This study developed lipid-core nanocapsules for encapsulating menthol, improving its solubility and thermal stability, and demonstrated their safety and rapid skin absorption in ex vivo tests, highlighting potential applications for cosmeceuticals.

This case report describes a 68-year-old woman with metastatic breast cancer who experienced significant improvement in visual acuity after stopping tamoxifen, which was associated with bilateral optic neuropathies.

This study found that ILK deficiency disrupts hair follicle development by impairing cell polarity and laminin-511 assembly, but these defects can be partially reversed with exogenous laminin-511.

This study found that citrullinated proteins, which are implicated in rheumatoid arthritis, were abundant in outer membrane vesicles from Porphyromonas gingivalis but nearly absent in mutants, validating their approach to citrullinated peptide identification.