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The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Zinc is crucial for nutrition, especially in patients with specific health conditions, and requires careful supplementation and monitoring.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

Skin grafts are effective for chronic leg ulcers, especially autologous split-thickness grafts for venous ulcers, but more data is needed for diabetic ulcers.

Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.

Finasteride has a higher risk of reproductive side effects than minoxidil.

Eating less can slow aging and help keep stem cells healthy by cleaning out damaged cell parts.

Electro-acupuncture may help treat PCOS in rats by changing brain DNA methylation.

We need better ways to test and understand SARMs to make safer and more effective treatments.

The conditions alopecia areata, primary sclerosing cholangitis, and ulcerative colitis may be linked by shared autoimmune and cell death mechanisms.

Scientists identified a unique type of human skin stem cell that could help with tissue repair.

Conditioned media from human amniotic fluid-derived stem cells helps skin heal and protects against aging from sun exposure.

Old drugs can be used for new treatments, saving time and money, but there are challenges like needing more evidence and legal concerns.

Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.

Different stem cells have benefits and challenges for tissue repair, and more research is needed to find the best types for each use.

A thorough initial check-up is essential before sperm banking to ensure the best chance of preserving good quality sperm.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Targeting colon cancer stem cells might lead to better treatment results.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

New methods to improve the healing abilities of mesenchymal stem cells for disease treatment are promising but need more research.

Thyrotropin-Releasing Hormone helps heal wounds in frog and human skin.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Mice lacking fibromodulin have disrupted healing patterns, leading to abnormal skin repair and scarring.