research Steroidal 5α-Reductase and 17α-Hydroxylase/17,20-Lyase (CYP17) Inhibitors Useful in the Treatment of Prostatic Diseases
Certain drugs that block specific enzymes can help treat prostate diseases.
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research Abiraterone and Spironolactone in Prostate Cancer: A Combination to Avoid
Don't combine abiraterone and spironolactone for prostate cancer treatment as it may worsen the disease.
research Receptors in Trichology: Hot Spots for Hair Regeneration
Vitamin D3 and its receptor are important for hair growth, and understanding receptors could help treat hair graying and skin cancer.
research New Insights Into Molecular Signaling Pathways And Current Advancements In Prostate Cancer Diagnostics And Therapeutics
New drugs and therapies targeting specific pathways show promise in treating advanced prostate cancer.
research BAYONET Trial: Staged Combination With Encorafenib, Binimetinib, Plus Cetuximab Following Encorafenib Plus Cetuximab for BRAF V600E-Mutant Metastatic Colorectal Cancer
The combination treatment showed a higher response rate but no significant survival benefits.
research Down-Regulation of Melanocortin Receptor Signaling Mediated by the Amino Terminus of Agouti Protein in Xenopus Melanophores
Agouti protein affects melanocortin receptors through competitive antagonism and receptor down-regulation.
research Androgen Metabolism in Hirsute Patients Treated with Cyproterone Acetate
Cyproterone acetate effectively reduced hair growth in hirsute patients by lowering androgen levels and altering androgen metabolism.
research Investigation of Follicle Stimulating Effect of Medical Cosmetic Remedies on the Androgen Alopecia Model in Rats
The cream-mask and gel-mask with certain plant extracts improved hair growth in rats similar to a common hair growth treatment.
research Gelatin Nanoparticles and Nanocrystals for Dermal Delivery
Improved methods create smaller, more effective gelatin nanoparticles for skin delivery, and new caffeine nanocrystals enhance absorption and effectiveness.
research Past, Present, and Future Treatment of Alopecia Areata
More research is needed to find the best long-term treatments for Alopecia Areata.
research Addressing Autoimmune and Immune-Mediated Skin Disease Burden in Women
The conclusion is that women are heavily affected by autoimmune skin diseases, face significant challenges, and need better research, treatments, and healthcare policies.
research Multimodal Recruitment for an Internet-Based Pilot Study of Ovulation and Menstruation Health
The study successfully gathered a diverse group of 438 women to understand the prevalence of polycystic ovary syndrome, with most participants recruited online and at community fairs.
research Common Variants in the Trichohyalin Gene Are Associated with Straight Hair in Europeans
Common variants in the Trichohyalin gene are linked to straight hair in Europeans.
research Proliferation, But Not Apoptosis, Is Associated With Distinct Beta-Catenin Expression Patterns in Non-Small-Cell Lung Carcinomas
Distinct β-catenin patterns are linked to cell growth, not cell death, in lung cancer.
research Nutritional Significance of Inositol and Biotin for the Pig
Biotin and inositol are crucial for pig health and growth.
research Alopecia Areata in 2 Patients Treated with Dupilumab: New Onset and Worsening
Dupilumab for atopic dermatitis may cause new or worsen existing alopecia areata.
research Production Rates of Testosterone and Dihydrotestosterone in Female Pattern Hair Loss
Women with female-pattern baldness produce more testosterone, but 5a-reductase inhibition treatment won't help.
research Melanocytes: The New Black
Melanocytes are crucial for skin pigmentation and can affect conditions like melanoma, vitiligo, and albinism, as well as hair color and hearing.
research Gene-Wide Association Study Between the Aromatase Gene (CYP19A1) and Female Pattern Hair Loss
Aromatase gene variation may increase female hair loss risk.
research Hirsutism: Evaluation and Treatment
Excessive hair growth can be assessed by history, exam, and blood tests, and treated with medication like dexamethasone, birth control pills, and spironolactone.
research Male Pattern Baldness: Current Treatments, Future Prospects
Current treatments for male pattern baldness include minoxidil and finasteride, with new options being developed.
research How Much Health Insurance Is Enough? Revisiting the Concept of Underinsurance
The document concludes that there is no clear definition of adequate health insurance, and a consistent method to measure underinsurance is needed.
research Management of Adverse Events and Other Practical Considerations in Patients Receiving Capecitabine (Xeloda)
Capecitabine is as effective as intravenous treatments with fewer side effects, but requires careful management of Hand-foot syndrome and patient education.
research Evidence for Two Independent Functional Variants for Androgenetic Alopecia Around the Androgen Receptor Gene
Two gene areas linked to male pattern baldness found, more research needed.
research A Comparative Study of Aldactone and Diane in the Treatment of Hirsutism
Aldactone was more effective in reducing hair growth in women with hirsutism than Diane, despite having less impact on hormone levels.
research Androgen Receptor Copy Number Variation and Androgenetic Alopecia: A Case-Control Study
No clear link between androgen receptor variation and hair loss, but more research needed.
research Effect of Finasteride on Lipid Profile in Individuals with Androgenetic Alopecia
Finasteride lowers good cholesterol, raises bad fats, and may increase heart disease risk.
research Harmless Herbs? A Review of the Recent Literature
Herbal remedies can cause adverse effects and need more safety research.
research Skin Melanocytes: Biology and Development
The paper concludes that understanding melanocyte development can help in insights into skin diseases and melanoma diversity.
research The PDGF/PDGFR Pathway as a Drug Target
The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.