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Diagnosing PCOS in teenagers should focus on signs of excess male hormones and not rely solely on ovarian ultrasound or irregular periods, and should be reassessed in adulthood.

Higher early lead exposure is linked to delayed puberty in girls.

Early diagnosis of Trichorhinophalangeal syndrome type 1 is crucial for treatment and was achieved through clinical examination and family history.

The environment around the time of conception can change the VTRNA2-1 gene in a way that lasts for years and may affect disease risk.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Most skin changes during pregnancy are harmless and temporary, but some can risk the fetus and need careful treatment.

A man developed oral hairy leukoplakia while on baricitinib, a medication for alopecia and arthritis, and doctors should watch for such side effects.

Elderly patients with CCCA were all African American with low vitamin D, but no iron or zinc deficiencies, and no hormonal imbalances compared to younger patients.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Dermal fibroblasts have adjustable roles in wound healing, with specific cells promoting regeneration or scar formation.

Nonclassic adrenal hyperplasia is a genetic condition that can cause early puberty and fertility problems, treated with specific steroids.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Early diagnosis and treatment of PCOS is crucial to reduce emotional distress and health risks.

Iron deficiency in menstruating women causes many health issues beyond anemia and needs early detection and treatment.

A complex X chromosome rearrangement can increase the risk of multiple autoimmune diseases.

Low selenium intake may delay puberty in boys but not in girls.

The three adipokines—leptin, adiponectin, and resistin—are present in various cells of normal dog skin.

Skin problems are common in Lupus patients and can indicate the disease's severity, requiring specific treatments and lifestyle changes.

Clinical signs of excess male hormones and actual hormone levels in the blood do not always match in women with polycystic ovary syndrome.

Ovulation disorders are a major cause of infertility and menstrual problems in women.

Plant adaptogens may help treat skin diseases and improve skin health, but more research is needed to fully understand how they work.

Paclitaxel is an effective cancer drug with side effects and potential new uses beyond cancer.

A 13-year-old boy with a rare scalp condition improved significantly with isotretinoin, minoxidil, oral steroids, and antiseptic shampoo.

Vitamin B5 and coenzyme A may help regulate the immune system and could improve treatments for chronic diseases and cancer.

Long-COVID has diverse, long-term health impacts, especially in young people.

A man with both Klinefelter syndrome and primary hyperparathyroidism showed a rare combination of symptoms and genetic patterns.

The study suggests that a specific gene variation and higher gene activity are linked to increased baldness in Egyptian men.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Biotin and biotinidase are essential to prevent health issues, and deficiencies require lifelong supplementation.