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The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Itraconazole is potentially effective for treating invasive aspergillosis, but more research is needed.

Removing part of the vitamin D receptor stops vitamin D from working properly.

New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.

Testing basal 17-HP levels is a good way to screen for nonclassic adrenal hyperplasia in women with high androgen levels.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Fibrinogen/LDL apheresis may improve speech perception in sudden hearing loss, especially for those with high fibrinogen and LDL levels.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Understanding hair follicle anatomy helps diagnose hair disorders.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Most women with PCOS have high levels of male hormones, and free testosterone is the best marker for this.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

The definition of Polycystic Ovary Syndrome may change with new research, and careful screening is key for managing the condition.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

The document concludes that rapid identification, isolation, and strict infection control are crucial to manage SARS outbreaks.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

We don't fully understand how sunlight damages different types of hair.

People with alopecia areata often have lower levels of vitamin D, zinc, and folate, but more research is needed to understand if supplements can help treat it.

Sub3 is essential for fungus adherence but not for skin invasion.

A special dressing called FEA-PCEI can speed up wound healing, reduce scars, and help grow new hair follicles, but only at the right dosage.

Different forms of hair loss drug can improve effectiveness.

Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.

The conclusion is that individual differences in COVID-19 severity are influenced by factors like age, sex, race, and genetics, which are important for personalized medicine.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Melatonin affects mouse skin and may regulate skin functions.