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Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.

Fingerprints form uniquely before birth due to specific genetic pathways and local signals.

Indian Hedgehog helps control skin cell growth and protects against aggressive skin cancer.

The study found stem cells in minor salivary glands that can differentiate and are involved in tumor formation when exposed to tobacco.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Melatonin protects skin against UV damage by regulating various cellular processes.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

New drugs are improving treatment for hormone-related diseases in small pets.

Aldesleukin can treat certain cancers and increase HIV patient CD4+ counts but often causes severe side effects.

Many adult women experience unexplained excessive hair shedding, often starting before age 40.

Apple polyphenol, especially oligomeric procyanidins, can reduce fat absorption and lower blood fat levels.

Telocytes might help with skin repair and regeneration.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Mitoxantrone with a corticosteroid helps manage symptoms for some advanced prostate cancer patients but doesn't extend life.

Oral contraceptives lower testosterone levels in women, especially those with certain genetic traits, and may be linked to increased breast cancer risk.

Epidermal stem cells have various roles in skin beyond just maintenance, including forming specialized structures and aiding in skin repair and regeneration.

ARL15 is important for fat cell development and the release of the hormone adiponectin.

Low-dose anti-androgen drugs and certain drug combinations are effective for hirsutism, and insulin sensitizers show promise, especially for those with polycystic ovarian syndrome.

The document concludes that hair loss is complex, affects many people, has limited treatments, and requires more research on its causes and psychological impact.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

Blocking β-catenin in skin cells improves hair growth during wound healing.

Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Non-binary transgender individuals need personalized hormonal treatments for better well-being and quality of life.

The document concludes that menopause should be seen as a natural part of aging and managed with personalized care and informed choices.

The document concludes that veterinary dermatologists need more experience and a better approach to treating skin diseases in nonhuman primates.

Lactoferrin helps mice grow hair by increasing cell growth and hair follicle development.

Scalp cooling to prevent hair loss from chemotherapy works for some but not all, and studying hair damage markers could improve prevention and treatment.