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180-210 / 1000+ results![Skin expression of mammalian target of rapamycin and forkhead box transcription factor O1, and serum insulin‐like growth factor‐1 in patients with acne vulgaris and their relationship with diet](/images/research/87ffc35a-0391-435f-9e7c-c734b34a3e32/small/14135.jpg)
research Skin expression of mammalian target of rapamycin and forkhead box transcription factor O1, and serum insulin‐like growth factor‐1 in patients with acne vulgaris and their relationship with diet
Eating a high-glycemic diet may worsen acne by increasing certain protein levels and expressions in the skin.
![Expression of steroidogenic enzymes in human sebaceous glands](/images/research/ca574fcf-c40b-4c77-93f5-8910e3339e98/small/31133.jpg)
research Expression of steroidogenic enzymes in human sebaceous glands
Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.
![Shedding Light on the Effects of Calorie Restriction and Its Mimetics on Skin Biology](/images/research/9684fd74-f1b9-47d0-afd9-ef5fab3e5e4d/small/17468.jpg)
research Shedding Light on the Effects of Calorie Restriction and Its Mimetics on Skin Biology
Eating fewer calories may slow skin aging and improve skin health through various biological changes.
research Sesn2/AMPK/mTOR signaling mediates balance between survival and apoptosis in sensory hair cells under stress
Sesn2 protects inner ear hair cells from damage by regulating certain cell survival pathways.
research OR2AT4, an Ectopic Olfactory Receptor, Suppresses Oxidative Stress-Induced Senescence in Human Keratinocytes
OR2AT4 helps reduce aging and cell damage in human skin cells.
![Effective amelioration of hepatic inflammation and insulin response in high fat diet-fed rats via regulating AKT/mTOR signaling: Role of Lepidium sativum seed extracts](/images/research/491f3c38-49f4-4cf8-bbb3-014ada0c4cbb/small/31055.jpg)
research Effective amelioration of hepatic inflammation and insulin response in high fat diet-fed rats via regulating AKT/mTOR signaling: Role of Lepidium sativum seed extracts
Lepidium sativum seed extracts helped reduce inflammation and improve insulin response in obese rats on a high-fat diet.
![Regulation of Mitochondrial Oxidative Metabolism by Tumor Suppressor FLCN](/images/research/5fb508bc-fec2-4f6f-98d6-0d0b4dc774b8/small/31158.jpg)
research Regulation of Mitochondrial Oxidative Metabolism by Tumor Suppressor FLCN
The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.
![Folliculin, the Product of the Birt-Hogg-Dube Tumor Suppressor Gene, Interacts with the Adherens Junction Protein p0071 to Regulate Cell-Cell Adhesion](/images/research/efb33c2a-6422-4511-b1ef-3492b17cdd28/small/31163.jpg)
research Folliculin, the Product of the Birt-Hogg-Dube Tumor Suppressor Gene, Interacts with the Adherens Junction Protein p0071 to Regulate Cell-Cell Adhesion
The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.
![Overexpression of hypoxia-inducible factor-1α in hidradenitis suppurativa: the link between deviated immunity and metabolism](/images/research/406d46e2-4083-41a7-860d-96ee95efb5d2/small/29940.jpg)
research Overexpression of hypoxia-inducible factor-1α in hidradenitis suppurativa: the link between deviated immunity and metabolism
Increased HIF-1α is linked to the inflammation and severity of hidradenitis suppurativa, suggesting treatments that lower HIF-1α could help.
![The aetiopathogenesis of acne vulgaris - what's new?](/images/research/d036a5fc-3833-4862-98c4-98fd9334a257/small/14393.jpg)
research The aetiopathogenesis of acne vulgaris - what's new?
Acne is caused by multiple factors including oil production, bacteria, inflammation, and possibly diet and environment.
![Activation of mTORC1 Signaling is Required for Timely Hair Follicle Regeneration from Radiation Injury](/images/research/c4214e21-6a3e-42e3-b812-e161ae6c5c67/small/4130.jpg)
research Activation of mTORC1 Signaling is Required for Timely Hair Follicle Regeneration from Radiation Injury
mTORC1 signaling needed for quick hair follicle recovery after radiation damage.
![Stem cell rejuvenation and the role of autophagy in age retardation by caloric restriction: An update](/images/research/551405ae-966b-461b-8d30-f2fa9ce9e7d1/small/19408.jpg)
research Stem cell rejuvenation and the role of autophagy in age retardation by caloric restriction: An update
Eating less can slow aging and help keep stem cells healthy by cleaning out damaged cell parts.
![Concise Review: The Plasticity of Stem Cell Niches: A General Property Behind Tissue Homeostasis and Repair](/images/research/97303a1a-0ce2-428a-8d26-f40f5ad1ca00/small/19731.jpg)
research Concise Review: The Plasticity of Stem Cell Niches: A General Property Behind Tissue Homeostasis and Repair
Stem cell niches are adaptable and key for tissue maintenance and repair.
![Topical L‐thyroxine: The Cinderella among hormones waiting to dance on the floor of dermatological therapy?](/images/research/055dcf38-7d12-4100-b23a-fd411dfbbaf6/small/23911.jpg)
research Topical L‐thyroxine: The Cinderella among hormones waiting to dance on the floor of dermatological therapy?
Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.
![N6-Methyladenosine modification (m6A) of circRNA-ZNF638 contributes to the induced activation of SHF stem cells through miR-361-5p/Wnt5a axis in cashmere goats](/images/research/bf90f706-701f-4dce-8343-d9cb040f91bb/small/30374.jpg)
research N6-Methyladenosine modification (m6A) of circRNA-ZNF638 contributes to the induced activation of SHF stem cells through miR-361-5p/Wnt5a axis in cashmere goats
A specific RNA modification in cashmere goats helps activate hair growth-related stem cells.
![Utjecaj prehrane i dodataka prehrani na acne vulgaris](/images/research/a45e491b-357e-4a7d-9e28-4ccb0044ec0a/small/27075.jpg)
research Utjecaj prehrane i dodataka prehrani na acne vulgaris
Diet and supplements can significantly affect acne, with some foods and nutrients reducing and others worsening it.
![T helper 17 cell/regulatory T-cell imbalance in hidradenitis suppurativa/acne inversa: the link to hair follicle dissection, obesity, smoking and autoimmune comorbidities](/images/research/5965766d-8bd6-40f0-860b-4f2df7704ad9/small/30122.jpg)
research T helper 17 cell/regulatory T-cell imbalance in hidradenitis suppurativa/acne inversa: the link to hair follicle dissection, obesity, smoking and autoimmune comorbidities
An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.
![Insulin Resistance and Skin Diseases](/images/research/0b4e06f6-1813-4481-9ed4-87c4223b038d/small/18704.jpg)
research Insulin Resistance and Skin Diseases
Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.
![Isotretinoin treatment upregulates the expression of p53 in the skin and sebaceous glands of patients with acne vulgaris](/images/research/9bc1177a-db54-4dcf-9bb5-79f63bc10618/small/13043.jpg)
research Isotretinoin treatment upregulates the expression of p53 in the skin and sebaceous glands of patients with acne vulgaris
Acne treatment with isotretinoin increases the presence of p53, a protein, in skin and oil glands, which may help reduce acne severity.
research Overview of Urethral Reconstruction by Tissue Engineering: Current Strategies, Clinical Status and Future Direction
The best method for urethral reconstruction is using hypoxia-preconditioned stem cells with autologous cells on a vascularized synthetic scaffold.
research PTEN Mediates Activation of Core Clock Protein BMAL1 and Accumulation of Epidermal Stem Cells
PTEN helps control the number and health of skin stem cells by working with the protein BMAL1.
research Antioxidant and Antiproliferative Activity of Finasteride against Glioblastoma Cells
![Adult female acne: Clinical and therapeutic particularities (Review)](/images/research/5917760d-cbfb-47bf-a98c-8bad56cbded4/small/17048.jpg)
research Adult female acne: Clinical and therapeutic particularities (Review)
Adult female acne is complex and requires a combination of treatments for effective management.
![Kartogenin regulates hair growth and hair cycling transition](/images/research/a6e0ca8f-cdc6-474c-8c1d-fa19b95e86d4/small/15772.jpg)
research Kartogenin regulates hair growth and hair cycling transition
Kartogenin may help treat hair loss by promoting hair growth and extending the hair growth phase.
![MicroRNA-149-Mediated MAPK1/ERK2 Suppression Attenuates Hair Follicle Stem Cell Differentiation](/images/research/e7e41b57-251e-493f-8e43-e5423f49dcd7/small/19191.jpg)
research MicroRNA-149-Mediated MAPK1/ERK2 Suppression Attenuates Hair Follicle Stem Cell Differentiation
Increasing miR-149 reduces hair follicle stem cell growth and hair development by affecting certain cell growth pathways.
research Commensal microbiome promotes hair follicle regeneration by inducing keratinocyte HIF-1α signaling and glutamine metabolism
research A preview of selected articles
The document concludes that DNA methylation and the mTOR pathway are important for stem cell function and could impact disease treatment.
![Analysis of changes in microRNA expression profiles in response to the troxerutin-mediated antioxidant effect in human dermal papilla cells](/images/research/0f9032d9-b7e3-416c-8b58-8b7eb5e26af3/small/14222.jpg)
research Analysis of changes in microRNA expression profiles in response to the troxerutin-mediated antioxidant effect in human dermal papilla cells
Troxerutin helps protect skin cells from oxidative stress and may be good for treating hair loss.
![HDAC6-dependent deacetylation of NGF dictates its ubiquitination and maintains primordial follicle dormancy](/images/research/a4befd5f-1217-4c29-84c1-66c05ae50985/small/36959.jpg)
research HDAC6-dependent deacetylation of NGF dictates its ubiquitination and maintains primordial follicle dormancy
HDAC6 helps keep ovarian follicles dormant, extending female fertility.