1 citations
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January 2010 in “Türkiye klinikleri tıp bilimleri dergisi” This case report describes a man with metastatic thymoma and diffuse pleural dissemination mimicking malignant mesothelioma, who also had alopecia areata without the presence of myasthenia gravis.
November 2025 in “Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin” This study examined 16 sporadic trichoblastic tumors and found that although one showed malignant transformation, clinical follow-up revealed no residual or metastatic disease. RNA sequencing indicated a high tumor mutational burden and absence of a UV-related signature, helping to distinguish these tumors from similar growths.
September 2025 in “Current Oncology” This review highlights the potential roles of long non-coding RNAs (lncRNAs) in malignant brain tumors, reporting that further research into their involvement in therapy resistance and cancer pathways could improve diagnosis and treatment outcomes.
October 2016 in “Journal of Case Reports” This study reports a case of an ovarian steroid cell tumor with malignant potential, presenting unusually with osteopenia and low weight instead of the expected virilizing symptoms.
April 2017 in “Australasian Journal of Dermatology” This article presents a planned trial comparing radiotherapy and imiquimod for lentigo maligna treatment, noting a lack of direct evidence supporting current therapies, and aims to inform future treatment guidelines.
85 citations
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May 2001 in “International Journal of Dermatology” This study observed that infections were the most common skin conditions in Ghana, while malignant and premalignant skin diseases were most common in the UK, highlighting different dermatological needs in each country.
38 citations
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July 1998 in “Journal of surgical oncology” This review discusses acquired hypertrichosis lanuginosa, a rare disorder often linked to internal malignancy, and reports no new clinical findings; the authors highlight proposed pathogenic mechanisms for lanugo hair overgrowth.
21 citations
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August 2011 in “BMB Reports” This study successfully established an immortalized human dermal papilla cell line that maintains characteristics of original cells without malignant transformation, potentially benefiting hair research.
1 citations
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March 2005 in “Zentralblatt für Gynäkologie” This case report describes a postmenopausal woman with hirsutism and androgenetic alopecia, where imaging ruled out malignancy and selective venous sampling indicated increased testosterone from the right adrenal vein, leading to a recommendation for right adrenalectomy and oophorectomy.
In this case study, researchers reported the first documented instance of malignant transformation of congenital triangular alopecia into basal cell carcinoma in a 48-year-old woman, underscoring the importance of assessing long-standing alopecic areas for malignancy.
August 2025 in “Frontiers in Immunology” This case report is the first to document the coexistence of bullous pemphigoid, malignant tumors, and alopecia areata in a patient, highlighting the complete resolution of skin lesions with dupilumab and spontaneous hair regrowth without disease-specific treatment.
February 2025 in “American Journal of Medical Case Reports” The case report highlights the diagnostic challenges of low-grade trichoblastic carcinoma, a rare malignant tumor often mistaken for benign lesions, in a 51-year-old female with immunocompromising conditions. Accurate diagnosis relied on histopathological examination, and achieving clear surgical margins was crucial to prevent recurrence.
March 2024 in “BMC cancer” This study reports that high expression of proteins ST14 and TMEFF1 in ovarian cancer correlates with higher tumor malignancy and worse prognosis, and reveals an interaction where ST14 regulates TMEFF1 to promote cancer cell proliferation, migration, and invasion.
This case report describes a 65-year-old postmenopausal woman with hyperandrogenism caused by a non-malignant ovarian Leydig cell tumor, which is a rare cause of virilization.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This case study describes a 41-year-old woman with a solitary thyroid nodule who underwent successful right hemithyroidectomy after initial suspicion of malignancy from ultrasound, later confirmed as benign colloid goiter via FNAC, highlighting the importance of thorough evaluation in thyroid conditions.
In this narrative case report, the authors discuss a patient recently diagnosed with an early-stage hematologic malignancy, highlighting her skepticism toward conventional medicine and preference for natural remedies over pharmaceutical treatments.
94 citations
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January 2007 in “Cutaneous and Ocular Toxicology” This review discusses the long-term cutaneous and ocular complications from sulfur mustard exposure in the Iranian population, identifying pruritus and malignant changes as significant issues and highlighting eye surface damage leading to visual decline.
30 citations
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February 1994 in “Journal of Cutaneous Pathology” This case study highlights that breast cancer may present as alopecia refractory to usual treatments, indicating the need for consideration of underlying malignancy in such cases.
18 citations
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April 2016 in “American Journal of Dermatopathology” This case series highlights that nail clipping can aid in early detection and surgical planning of onychomatrical tumors by distinguishing between benign and potentially malignant growths based on the cavities' average dimensions.
17 citations
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January 2014 in “Journal of Oral and Maxillofacial Pathology” This case report establishes the diagnosis of seborrheic keratosis in an elderly Indian woman based on histopathological examination, highlighting its potential to mimic malignant tumors and emphasizing the importance of differential diagnosis.
14 citations
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December 2010 in “Seminars in Oncology” This review discusses the diagnostic challenges of androgen and estrogen-secreting adrenal tumors and highlights that the presence of metastases is the most reliable indicator of malignancy; it reports no new clinical findings.
9 citations
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September 2021 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” This review examines the cutaneous manifestations of systemic diseases, including metabolic, cardiovascular, renal, gastrointestinal, and malignant conditions, as well as updates on skin signs of COVID-19, without presenting new study results.
7 citations
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April 2000 in “Archives of Pathology & Laboratory Medicine” This case report documents the first observed cytologic changes, specifically cytoplasmic vacuolization, in finasteride-associated gynecomastia, which should not be misinterpreted as evidence of malignancy.
7 citations
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April 2000 in “Archives of Pathology & Laboratory Medicine” This case report describes the first observed cytologic changes in gynecomastia associated with finasteride therapy, emphasizing that cytoplasmic vacuolization should not be mistaken for malignancy.
6 citations
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July 2013 in “Archives of Plastic Surgery” This article explains that proliferating trichilemmal tumors, originating in the hair follicle, can exhibit low-grade malignant potential, and recommends wide excision to minimize recurrence risk, but reports no new clinical findings.
5 citations
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June 2016 in “University of Zagreb University Computing Centre (SRCE)” This study observed that canine follicular tumors are an uncommon type of skin neoplasia in Croatian dogs, often benign but with a small percentage presenting malignancy, and vary based on the breed's hair growth type.
3 citations
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June 2021 in “Clinical, Cosmetic and Investigational Dermatology” This study highlights the importance of dermoscopic examinations in accurately diagnosing skin cancer, which can be mistaken for benign seborrheic keratosis, emphasizing the need for trained interpretation to avoid missing malignant lesions.
2 citations
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June 2025 in “Preprints.org” This review highlights the potential of amphiregulin as a therapeutic target, noting its role in both fibrotic and malignant diseases, and discusses promising early findings but reports no new clinical results.
2 citations
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November 2018 in “Cell Stem Cell” This study reported that wound-resident mesenchymal cells can be reprogrammed to generate epithelial tissues, aiding in the closure of large, non-healing ulcers without signs of malignant transformation.
2 citations
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January 2018 in “Open journal of stomatology” This study found that trichohyalin is expressed in cancerous tongue epithelial cells, while plectin-1 expression may indicate malignancy.