20 citations,
August 2016 in “International Journal of Cancer” Men with male pattern baldness have a higher risk of certain skin cancers, especially on the scalp.
19 citations,
January 2001 in “Dermatology + psychosomatics” The review concluded that male pattern baldness is mostly seen negatively, affecting attractiveness and social appeal.
2 citations,
January 2009 in “Journal of the Royal Society of Medicine” Art often hides male pattern baldness, but van Gogh's work links it to depression.
April 2012 in “The Journal of Urology” Male pattern baldness may predict prostate cancer risk.
2 citations,
September 2007 Surgical hair restoration involves moving hair from a non-balding area to a balding area, with the transplanted hair not subject to male pattern baldness. Medications can slow hair loss and regrow some hair, but successful treatment needs careful planning, skill, and ethical responsibility due to progressive hair loss and limited donor hair.
17 citations,
December 2004 in “The Journal of Men's Health & Gender” Male pattern baldness involves hormone-related hair thinning, shorter hair, and inflammation.
February 2021 in “Journal of Investigative Dermatology” Hair loss in male pattern baldness is linked to changes in specific genes and proteins that affect hair growth and scalp health.
1 citations,
July 2022 in “British Journal of Dermatology” Targeting specific genes in certain pathways may help treat male pattern baldness.
June 2016 in “International journal of recent surgical and medical science” Early balding in men is linked to metabolic syndrome, so screening is important for prevention.
22 citations,
May 2002 in “Skin Research and Technology” CE-PTG detects early hair follicle issues in balding areas, helping measure male hair loss.
15 citations,
May 2010 in “Actas Dermo-Sifiliográficas” Balding men have higher heart disease risk.
6 citations,
January 2022 in “Journal of Investigative Dermatology” Male pattern baldness is linked to higher levels of a certain receptor in the scalp, which leads to the shrinking of blood vessels and hair loss. Early treatment targeting this receptor could be more effective.
Balding men are more likely to have metabolic syndrome.
Men with both baldness and scalp psoriasis often don't have psoriasis on bald spots.
34 citations,
February 1999 in “Journal of Dermatological Science” Minoxidil boosts enzymes that help hair growth.
34 citations,
February 1992 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride and minoxidil together promote hair growth better than either alone.
24 citations,
January 2010 in “Endocrine Regulations” Taking 1mg of finasteride daily can mildly improve metabolic health and glucose regulation in men with male pattern baldness.
May 2017 in “Journal of The American Academy of Dermatology” The treatment increased hair follicle counts and is potentially effective for male hair loss without serious side effects.
57 citations,
January 2004 in “Journal of Endocrinology” Baldness caused by male hormones in female-to-male transsexuals doesn't increase the risk of heart disease.
14 citations,
December 2003 in “Medical Hypotheses” Male-pattern baldness might be caused by the effect of hormones on scalp blood vessels.
9 citations,
November 1993 in “Journal of The American Academy of Dermatology” Some men can have female pattern baldness without hormonal abnormalities or signs of feminization.
2 citations,
January 2004 in “Enshou saisei” Male pattern baldness is caused by certain cells in hair follicles and could potentially be treated by targeting a specific growth factor, TGF-β1.
20 citations,
August 2005 in “Journal of Cutaneous Pathology” The protein ARA70/ELE1 is involved in male pattern baldness, and lower levels of its short form may lead to hair thinning.
23 citations,
December 1991 in “Annals of the New York Academy of Sciences” Balding scalps slow down hair growth.
32 citations,
March 1987 in “Journal of The American Academy of Dermatology” Using minoxidil on balding men's scalps can increase hair growth, according to a 12-month study.
March 1998 in “Journal of dermatological science” Protease Nexin-1 is found in human hair growth cells and is affected by male hormones.
27 citations,
September 1999 in “Journal of Investigative Dermatology” Human skin cells contain Protease Nexin-1, and male hormones can decrease its levels, potentially affecting hair growth.
3 citations,
June 2009 in “Journal of The European Academy of Dermatology and Venereology” Sparse hairs below frontal hairline can indicate early male balding.
June 1996 in “Archives of Dermatology” Using a mix of finasteride and minoxidil can significantly regrow hair in men with pattern baldness.
227 citations,
January 1998 in “Journal of Endocrinology” Cells from balding scalps have more androgen receptors than cells from non-balding scalps.