170 citations
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May 1979 in “The journal of pediatrics/The Journal of pediatrics” This report describes two sisters with rickets and alopecia unresponsive to high doses of vitamin D2, where oral phosphorus supplements led to significant clinical improvement.
55 citations
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December 1987 in “Archives of Dermatology” This review discusses two genetic disorders affecting biotin metabolism, each resulting in distinctive skin and hair manifestations, and outlines the associated serious metabolic complications.
April 2026 in “Clinical Case Reports” This case study suggests that "celiac hepatitis" should be considered in patients with unexplained liver dysfunction, highlighting the importance of recognizing celiac disease to avoid misdiagnosis and allow reversal of liver abnormalities with proper treatment.
April 2026 in “Diagnostics” This case report identifies collagenous gastritis as the cause of chronic gastrointestinal symptoms in a 27-year-old male, characterized by severe chronic inactive gastritis and a distinctive subepithelial collagen band.
May 2024 in “Our Dermatology Online” In this case report, a mother and daughter with celiac disease experienced hair loss as their primary or initial extraintestinal symptom, highlighting the potential link between celiac disease and alopecia.
November 2019 in “European journal of internal medicine” This report documents a case of Cronkhite-Canada Syndrome in a 56-year-old Laotian man, who successfully improved with vitamin supplementation and medical treatment after experiencing weight loss, alopecia, and gastrointestinal polyposis.
8 citations
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December 2019 in “Molecular genetics and metabolism reports” This study found that early biochemical screening and molecular confirmation are crucial for distinguishing profound from partial biotinidase deficiency, which supports timely treatment and management in symptomatic children.
1 citations
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January 2013 in “Nasza Dermatologia Online” This case report describes reversible hypopigmentation of hair in a child due to vitamin B12 deficiency, which improved after vitamin B12 supplementation.
May 2016 in “Mayo Clinic proceedings” This case report describes a 26-year-old man whose abdominal pain and other symptoms led to a diagnosis of celiac disease-induced small-bowel intussusceptions, which resolved with a gluten-free diet.
November 2025 in “Scientific Reports” This study found that metabolic dysfunction-associated steatotic liver disease is linked to a higher risk of androgenetic alopecia, especially in women and individuals with certain lifestyle patterns.
February 2026 in “Frontiers in Pediatrics” This case report describes a 7-year-old girl initially misdiagnosed with SMA syndrome, but later found to have a gastric trichobezoar via EGD, highlighting the diagnostic challenges in children with nonspecific symptoms.
29 citations
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December 1989 in “The journal of nutrition/The Journal of nutrition” This study found that intestinal uptake of pantothenic acid in mice was not affected by dietary levels but may increase slightly in late-stage deficiency, though likely not significantly.
15 citations
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November 2009 in “Journal of diabetes and its complications” This case highlights the potential link between type 1 diabetes, pernicious anemia, and alopecia areata universalis, suggesting clinicians should monitor for pernicious anemia in such patients.
May 2022 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, patients who underwent Roux-en-Y gastric bypass surgery lost significant weight and improved obesity-related complications, but experienced increased hair loss and needed careful calcium and protein management.
14 citations
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October 1978 in “Archives of Dermatology” This report describes two cases where acquired zinc deficiency was associated with skin symptoms like hair loss and eczema, suggesting a recognizable syndrome in zinc-deficient patients.
6 citations
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April 2012 in “PubMed” This case report describes a 33-year-old Indian male with Cronkhite-Canada syndrome who experienced complete symptom recovery within 5 months after starting a high protein diet, proton pump inhibitors, and zinc-vitamin supplements.
November 2025 in “Journal of Saidu Medical College Swat” In this case report, a 2.5-year-old boy with biotinidase deficiency, initially misdiagnosed due to overlapping symptoms, showed dramatic improvement in several clinical areas after starting biotin supplementation, but persistent sensorineural hearing loss underscored the importance of early diagnosis for preventing irreversible complications.
June 2022 in “Journal of medical science and clinical research” This case report describes a weaning infant diagnosed with Brandt syndrome displaying periorificial dermatitis and rapid symptom improvement following zinc supplementation.
2 citations
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January 2018 This article reports the first case of perforating necrobiosis lipoidica in Colombia and the 19th case worldwide in diabetic patients.
This case study describes a 34-year-old woman with low serum zinc levels, skin lesions, and hair loss, potentially linked to excessive alcohol consumption.
2 citations
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March 2020 in “JAAD case reports” This article discusses the various clinical manifestations of kwashiorkor, resulting from severe protein malnutrition, and reports no new research findings.
December 2009 in “Pediatrics in review” This case study describes a 17-year-old girl initially thought to be experiencing a Crohn disease exacerbation, but ultimately found to have a trichobezoar causing small bowel obstruction.
1 citations
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July 2017 in “PubMed” This study describes two Danish cases of Cronkhite-Canada syndrome presenting with malnutrition and gastrointestinal issues; both patients underwent successful treatment and remission after developing colonic adenocarcinomas.
April 2024 in “International Journal of Advanced Research” In this case-control study, researchers observed that vitamin B12 deficiency was significantly associated with diffuse hair loss and muco-cutaneous pigmentation in patients, suggesting these may serve as clinical markers for dermatologists to consider when diagnosing vitamin B12 deficiency.
March 1983 in “Annals of Internal Medicine” This letter to the editor mentions reports of hair loss potentially related to 5-aminosalicylic acid enemas, but suggests it may be due to telogen effluvium from severe inflammatory bowel disease rather than a direct effect.
2 citations
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May 2007 in “Pediatrics in Review” This case study reports a teenage boy with juvenile polyposis syndrome, presenting with microcytic anemia, growth failure, and rectal bleeding, leading to the diagnosis following colonoscopy and histologic examination of colonic polyps.
9 citations
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October 2015 in “Postgraduate Medical Journal” This case study illustrates the classic dermatological signs of scurvy in a man with unusual dietary habits, showcasing the importance of recognizing and treating vitamin C deficiency in marginalized populations.
1 citations
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January 2020 in “Journal of Crohn's and colitis” In this case series, researchers observed that patients with inflammatory bowel disease often experienced vitamin C deficiency, which was linked to symptoms of scurvy, highlighting the need for dietary counseling.
10 citations
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January 2016 in “ACG Case Reports Journal” This case report describes a 73-year-old male with numerous colon polyps whose long-term use of Cape Aloe likely caused melanosis coli, which helped highlight the polyps' locations.
February 2026 in “Pediatrics in Review” This case report describes an infant with congenital hyperinsulinism linked to a genetic mutation in the ABCC8 gene, illustrating challenges in managing persistent hypoglycemia despite medical interventions, leading to a near-total pancreatectomy.