Case Number 19 of Perforating Necrobiosis Lipoidica Worldwide
January 2018
TLDR The document reports the 19th global case of a rare skin condition in a patient from Colombia.
The document discusses a rare condition known as perforating necrobiosis lipoidica, which is characterized by the elimination of necrobiotic collagen through the epidermis, typically in diabetic patients. The lesions resemble those of classic necrobiosis lipoidica but are distinguished by keratotic plugs over the borders of the atrophic yellow plaques. The condition is caused by necrotic collagen in the upper dermis that leads to inflammation and subsequent rupture through the hair follicle wall or through abnormal channels to the skin surface. The paper emphasizes the significance of the first reported case in Colombia, marking it as the 19th case documented globally.
