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This study found that rice bran supercritical CO₂ extract was classified as a non-irritant for ocular use but a moderate irritant for dermal use in rabbits and guinea pigs.

This study found that miR-203a-3p downregulates Smad1, promoting the differentiation of loureirin A-induced hair follicle stem cells, suggesting it could be a potential therapeutic target for skin wound healing.

This study investigated the effects of heat-treated Limosilactobacillus fermentum LM1020 on hair growth and reported increased hair density, improved cellular activity, and beneficial scalp microbiota changes in patients with androgenetic alopecia over 24 weeks.

This study identified a novel missense MAFB variant in a family with some unaffected members, suggesting incomplete penetrance and the potential influence of modifier genes, epigenetic mechanisms, or environmental factors on MCTO phenotype.

Among in vitro and in vivo models, this study found that Miscanthus sinensis var. purpurascens flower extract may promote hair growth, potentially by modulating growth factor expressions and facilitating earlier hair follicle transitions in treated mice.

This study found that overexpression of antizyme in mice with activated MEK reduced skin tumor growth by inhibiting putrescine accumulation, slowing cell growth, and increasing G2/M transit time.

JW0061 may be a new treatment for hair loss by promoting hair growth through WNT signaling.

AMP-303 injections can increase hair growth in androgenetic alopecia with minimal side effects.

In this pilot study of Indonesians, the rs1998076 genetic variant was not significantly linked to androgenetic alopecia, though the GG genotype showed a non-significant trend toward higher odds, while clinical factors like age and hypertension were correlated with increased risk.

This study reports that the DMI3 gene, essential for nodule formation in legume-rhizobial symbiosis, encodes a calcium/calmodulin-dependent protein kinase, highlighting its role in multiple plant symbioses.

This study identified mefloquine as a potent inducer of lethal ER stress that effectively eliminated vemurafenib-resistant and sensitive melanoma cells, suggesting its potential for repurposing as a melanoma treatment.

This study found that ALRN-6924, a clinical-stage dual inhibitor, can selectively protect human scalp hair follicles from paclitaxel-induced toxicity and damage by inducing transient cell cycle arrest in healthy cells without affecting cancer cells, potentially reducing chemotherapy-induced alopecia.

This study found that the AR-E211 A allele is associated with a lower risk of both metastatic prostate cancer and androgenetic alopecia in an Australian population.

P-3074 effectively blocks scalp DHT better than oral finasteride.

This study found that OPC-17116 can be reliably detected in hair, suggesting it can serve as an index of drug exposure and a time-marker in hair analysis.

This study found that among ten Curcuma aeruginosa accessions, the MD accession showed the highest anticancer activity against MCF-7 cells, suggesting its potential for pharmaceutical development.

This study found that the addition of SPACE peptide significantly enhanced the penetration of amniotic membrane stem cell metabolites in mice, with only very mild irritation observed.

This study found that a newly created biomimetic microneedle platform effectively expedited wound repair in diabetic animal models by reducing inflammation, enhancing angiogenesis, and promoting skin regeneration through targeted drug delivery and immune response modification.

In this study, RT1640 was found to promote hair pigment system regeneration and expand melanocyte stem cell pools in a mouse model, suggesting potential applications for aging-related hair disorders.

This study concluded that coat damage in captive rhesus macaques is unlikely caused by parasitic, bacterial, or mycotic infections but may be linked to environmental or behavioral factors affecting hair growth.

In this study, AS101 combined with chemotherapy significantly reduced the severity of chemotherapy-induced alopecia in non-small-cell-lung-cancer patients and may involve immune mechanisms related to IL-1 and PGE2.

In this study, researchers presented a novel therapeutic approach for androgenetic alopecia combining AR-PROTAC degradation with regenerative strategies and evaluated the potential of GT20029 as a topical treatment, proposing a three-phase protocol and future research hypotheses.

This study found that rice bran ash extract enhanced melanin biosynthesis-related protein expression in a 3D hair follicle-like tissue model and hair follicle organ culture, suggesting potential for future research in melanogenesis.

In this study, researchers created a hydrogel that reduces oxidative stress and releases a pro-angiogenic drug in response to enzyme activity, which accelerated healing and improved tissue regeneration in chronic diabetic wounds during in vivo experiments.