research Thymic Mesenchymal Cells Have a Distinct Transcriptomic Profile
Thymic mesenchymal cells have unique gene expression that supports their specific functions in the thymus.
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research Improved Humoral Immunity and Protection Against Influenza Virus Infection With a 3D Porous Biomaterial Vaccine
A new vaccine using a porous scaffold boosts immunity and protects against the flu better than traditional methods.
research Denosumab-Induced Alopecia Areata with Lichenoid Eruption
Denosumab, a bone loss treatment, may cause hair loss and skin reactions due to immune system effects.
research Inhibition of a Signaling Modality Within the Gp130 Receptor Enhances Tissue Regeneration and Mitigates Osteoarthritis
Blocking a certain signal in the gp130 receptor can improve tissue healing and lessen osteoarthritis symptoms.
research ST14 Interacts With TMEFF1 and Is a Predictor of Poor Prognosis in Ovarian Cancer
High levels of ST14 and TMEFF1 proteins in ovarian cancer are linked to worse patient outcomes and may be a new treatment target.
research Molecular Mechanisms of Y Chromosome Loss and UTY Gene Activity
Loss of the Y chromosome and UTY gene activity increases cancer risk in men.
research Leukemia Cutis of the Scalp Masquerading as Kerion in a Child
Leukemia can sometimes appear as unusual skin issues in children.
research Androgenetic Alopecia – Update 2022
research Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche
Low oxygen areas help maintain and protect blood stem cells by using a simple sugar breakdown process for energy and managing their activity levels.
research JAK Inhibitors in Dermatology: The Promise of a New Drug Class
JAK inhibitors show promise for treating skin conditions like eczema, hair loss, and psoriasis.
research The Stem Cell Niche in Regenerative Medicine
Targeting and modifying the stem cell niche can improve regenerative therapies.
research In Human Skin, UVB Initiates Early Induction of IL-10 Over IL-12 Preferentially in the Expanding Dermal Monocytic/Macrophagic Population
UVB exposure in human skin causes macrophages to produce more IL-10 and less IL-12, leading to immunosuppression.
research Targeting Integrin Pathways: Mechanisms and Advances in Therapy
New therapies are being developed that target integrin pathways to treat various diseases.
research An Essential Role for RXRα in the Development of Th2 Responses
RXRα is crucial for proper immune response and links diet to immune function.
research The Immunological Impact of IL-1 Family Cytokines on the Epidermal Barrier
IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.
research Skin - A Vast Organ with Immunological Function (Review)
The skin is a large organ that plays a role in the immune system.
research Sex Hormones in SARS-CoV-2 Susceptibility: Key Players or Confounders?
Sex hormones' effects on COVID-19 are unclear and more research is needed to understand their potential as treatment.
research Off-Label Uses of Retinoids in Dermatology
Retinoids are effective for various skin conditions and hair loss but have serious side effects, so low doses are recommended.
research Wnt4 Increases the Thickness of the Epidermis in Burn Wounds by Activating Canonical Wnt Signalling and Decreasing Cell Junctions Between Epidermal Cells
Wnt4 protein makes the outer skin layer thicker in burn wounds by turning on a specific healing pathway and loosening the connections between skin cells.
research Adipose Tissue Remodeling via TSLP-Mediated IL-4/IL-13 Signaling: Implications for Atopic Dermatitis and Skin Barrier
TSLP affects atopic dermatitis by increasing sebum and reducing fat through IL-4/IL-13 signaling.
research Emerging Trends and Focus in Human Skin Microbiome Over the Last Decade: A Bibliometric Analysis and Literature Review
Research on the human skin microbiome has grown, focusing on skin health and diseases, with more studies needed on antibiotic resistance and AI applications.
research New Frontiers in CRISPR/Cas9 Delivery Systems for Gene Editing
Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.
research Genetics of Hidradenitis Suppurativa
Hidradenitis Suppurativa has genetic links, with certain gene mutations more common in patients and a third of cases having a family history.
research Isolation and Characterization of Recombinant Murine Wnt3a
Scientists successfully purified a protein called Wnt3a, which is involved in processes like hair growth, but the overall yield was low, suggesting more work is needed to improve this.
research Multiple Sclerosis: Side Effects of Interferon Beta Therapy and Their Management
The article suggests managing interferon beta therapy side effects in MS with dose adjustments, medications, and patient education.
research Chromatin Remodeler Lymphoid-Specific Helicase (Lsh) Is a Critical Determinant Controlling Postnatal Epidermal Growth, Differentiation, and Response to Injury
Lymphoid-specific helicase (Lsh) is crucial for skin growth, change, and healing after injury.
research A Case of Cutaneous Lymphoid Hyperplasia After Hyaluronic Acid Filler Injection and Fat Grafting
Hyaluronic acid filler and fat grafting can cause rare skin complications.
research Inducible Skin-Associated Lymphoid Tissue (iSALT) Detected in Scalp Treated with Topical Immunotherapy for Alopecia Areata
Topical immunotherapy for alopecia areata may work by creating immune cell clusters in the skin.
research A Rare Case of Isolated Pulmonary Involvement in Lymphoid Variant Hypereosinophilic Syndrome
A man with a rare lung-focused form of hypereosinophilic syndrome improved with steroid treatment.
research Hapten-Induced Lymphadenosis Benigna Cutis Secondary to Squaric Acid Dibutylester Sensitization for Alopecia Areata
Squaric acid dibutylester for alopecia areata can cause benign skin lymphoid growths.