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TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

A protein from certain immune cells is key for new hair growth after skin injury in mice.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

The Rotterdam Study aims to understand various diseases in older adults.

Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.

PGD2 stops hair growth and is higher in bald men with AGA.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Lactate production is important for activating hair growth stem cells.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Visible light can damage skin and most sunscreens don't block it well; more research is needed on its effects and protection methods.

The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Targeted cancer therapies often cause serious skin problems that need careful management.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.