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Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

α3β1-integrin is crucial for maintaining normal hair follicle shape and function but not needed for the development of the surrounding skin.

Targeted cancer therapies have a significant but lower risk of causing hair loss compared to chemotherapy.

Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.

Lupus can affect the scalp and nails, often causing hair loss and nail damage, and needs early aggressive treatment to prevent permanent damage.

Special immune cells called Regulatory T cells help control skin inflammation and repair in various skin diseases.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Targeted cancer therapies often cause skin problems that need careful management to improve patient quality of life and treatment success.

Taking L-cystine and vitamin B6 can prevent hair loss caused by smoke in mice.

CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.

Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.

New drug delivery methods can make natural compounds more effective and stable.

Minoxidil lowers blood pressure, increases heart rate, and improves blood flow in dogs.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Skin and hair can regenerate after injury due to changes in gene activity, with potential links to how cancer spreads. Future research should focus on how new hair follicles form and the processes that trigger their creation.

Women with PCOS are more likely to have fatty liver disease and worse metabolic health.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Aromatase inhibitor therapy for breast cancer increases the risk of hair loss and thinning.

Cell aging can be both good and bad for tissue repair.

Long-term fluticasone treatment does not harm the immune system in horses with heaves.

Transit-amplifying cells are crucial for tissue repair and can contribute to cancer when they malfunction.

Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.

Mice lacking fibromodulin have disrupted healing patterns, leading to abnormal skin repair and scarring.

Mice without certain skin proteins had abnormal skin and hair development.

Targeting CD200 could be a new treatment for rheumatoid arthritis.

Skin organoids are a promising new model for studying human skin development and testing treatments.

Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.