Prevalence of Non-Alcoholic Fatty Liver Disease in Women with Polycystic Ovary Syndrome and Its Correlation with Metabolic Syndrome

    May 2015 in “ Arquivos De Gastroenterologia ”
    Mariana Drechmer Romanowski, Mônica Beatriz Parolin, Alexandre Coutinho Teixeira de Freitas, Mauri José Piazza, Jorgete Basso, Almir Antonio Urbanetz
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    TLDR Women with PCOS are more likely to have fatty liver disease and worse metabolic health.
    The study investigated the prevalence of non-alcoholic fatty liver disease (NAFLD) in 101 women with polycystic ovary syndrome (PCOS) compared to a control group of 30 women. It was found that 23.8% of the women with PCOS had NAFLD, significantly higher than the 3.3% in the control group. Although the prevalence of metabolic syndrome was similar between the PCOS group (32.7%) and the control group (26.6%), the subgroup of women with both PCOS and NAFLD had a higher prevalence of metabolic syndrome, with 75% meeting the NCEP/ATPIII criteria and 95.8% meeting the International Diabetes Federation criteria. These women also had higher age, weight, BMI, abdominal circumference, and glucose tolerance test results. The study concluded that there is a high prevalence of NAFLD in women with PCOS, and those with both conditions are more likely to have worse metabolic profiles and a higher risk of developing metabolic syndrome.
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