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Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.

Some common medications like metformin, insulin, and ACE inhibitors can lower PSA levels, while statins don't, and low dose finasteride significantly reduces PSA.

A 37-year-old man with hair loss and skin issues was successfully treated with oral antibiotics, highlighting the need for early treatment. Long-term care includes low-dose antibiotics and avoiding caps and wigs.

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Low SULT activity in hair follicles leads to better response to oral minoxidil for hair loss.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

Isotretinoin at low doses effectively treats facial papules in frontal fibrosing alopecia.

Diphenyl cresyl phosphate has low toxicity but can harm the liver, kidneys, adrenal glands, and testicles at high doses.

Eating too much selenium can cause bad breath, hair loss, and nail changes, with harmful effects starting at low daily doses.

Retinoids are effective for various skin conditions and hair loss but have serious side effects, so low doses are recommended.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Melanocytes are crucial for skin pigmentation and can affect conditions like melanoma, vitiligo, and albinism, as well as hair color and hearing.

Lifestyle changes and weight loss are key for treating PCOS-related metabolic issues and infertility, with various medications available for specific symptoms.

New treatments for Dissecting cellulitis show promise, but more research is needed to understand the disease and establish a standard treatment plan.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

Hormonal treatments can improve acne, but they come with potential side effects and risks.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

The cause of atypical Cushing's syndrome in dogs, possibly linked to sex hormones, is not yet proven.

The conclusion is that removing both ovaries is the best treatment for excess male hormones in postmenopausal women, with medication as another option, and managing insulin resistance is important for diagnosis and treatment.

New treatments for hair loss are showing promise due to better understanding of genetics and the immune system.

Birth control pills can help reduce mild to moderate acne in women.

Oral minoxidil can increase or maintain hair thickness in most people with lichen planopilaris, with mild side effects.

New therapies for alopecia areata show potential but need more research.

AGA treatments like minoxidil and LLLLT are safe and effective for gender minority patients.

Men can experience female pattern hair loss, needing different treatments.

New treatments for hair loss are emerging, and doctors need to learn how to use them effectively.

More people are seeing dermatologists for hair and scalp problems now than in the past.

New and existing treatments for hair loss show promise, with some being more effective for men and others for women.

Direct-to-consumer teledermatology platforms have financial conflicts of interest and lack proper patient care and follow-up.