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The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

The article concludes that correctly diagnosing systemic causes of hair loss requires a detailed clinical evaluation and a systematic diagnostic approach.

Metformin helps regulate menstrual cycles, induce ovulation, and improve pregnancy outcomes in women with PCOS.

The document concludes that PCOS has a strong genetic component, but more research is needed to fully understand the specific genes involved.

Genetic counselors should be culturally skilled and aware of transgender patients' unique health risks and needs.

New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.

Treating excessive hair in women requires a holistic approach, including medical, aesthetic, and emotional support.

The document concludes that proper diagnosis and tailored long-term treatment can effectively manage androgenic disorders in women, improving patient care outcomes.

The new FDA labeling rules provide more detailed drug safety information for pregnant and breastfeeding women, but more data is needed on the risks of many dermatologic drugs.

Healthcare providers need better education and policies to serve transgender individuals effectively.

Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.

DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.

Blocking enzymes that help the virus enter cells could be a promising way to treat COVID-19.

Finasteride effectively treats central serous chorioretinopathy.

Treat pattern hair loss with finasteride and topical minoxidil.

The document concludes that various cosmetic and drug treatments are available for hirsutism, and some new drugs show promise.

Finasteride helps protect brain in old male rats.

Women with polycystic ovary syndrome have a higher risk of certain fractures.

Finasteride affects brain processes related to neurotransmission and metabolism, potentially helping with neuropsychiatric conditions.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.

Healthcare providers need better understanding and cultural sensitivity to improve care for transgender patients with kidney failure needing transplants.

Alternative treatments show promise for hair growth beyond traditional methods.

Women with PCOS-related infertility can often conceive with treatments like clomiphene and metformin, but managing pregnancy complications is important.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

Women with Systemic Lupus Erythematosus should have closely monitored pregnancies and avoid certain medications to improve their pregnancy outcomes.

Testosterone therapy can modestly improve sexual function in menopausal women but should be used cautiously and is not recommended for routine measurement in sexual dysfunction or hirsutism.

The document explains that hirsutism, often caused by hormonal issues, can be managed with treatment to improve both physical appearance and mental health.

Women with nonclassic congenital adrenal hyperplasia experience more sexual dysfunction and distress.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.