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LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.

Ozone therapy might improve cancer treatment and reduce its side effects.

A specific RNA molecule, circCOL1A1, affects the growth and quality of goat hair by interacting with miR-149-5p and influencing cell growth pathways.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.

The document listed medical job ads and guidelines for breast cancer screening.

New method finds genetic links between Type 2 Diabetes and Prostate Cancer not seen before.

Dietary essential fatty acids improved skin and hair conditions and partially corrected fat composition in diabetic mice.

Finasteride and dutasteride may cause metabolic issues like liver disease and diabetes.

Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.

Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

Caffeic acid helps protect rats from the harmful effects of acrylamide.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Stem cell niches are adaptable and key for tissue maintenance and repair.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

The document concludes that skin and nail changes can indicate various underlying health conditions.

Cadmium chloride pollution can cause skin disorders, speed up aging, and prevent hair growth.

Origanum vulgare leaf extract reduces liver and kidney damage caused by finasteride in mice.

Platelet-rich plasma might help tissue regeneration in dentistry, but results vary and more research is needed.

Choline and biotin are important for liver health and preventing certain deficiencies in animals, and more research is needed to understand their benefits in humans.

Eating plants from polluted areas can cause liver and kidney damage in rats due to toxic metals.