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Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.

The document concludes with guidance for doctors on diagnosing and treating hirsutism effectively and safely.

The combination of cyproterone acetate and testosterone enanthate is highly effective in preventing sperm production and could be a good reversible male contraceptive.

Ketoconazole reduced hair growth and improved acne in women, but caused side effects needing careful monitoring.

The research found that polycystic ovary syndrome (PCOS) has two distinct types, with one having more severe hormone and insulin issues.

Finasteride reduces hair growth and is safe for women with excessive hair.

All treatments reduce hair growth; low dose flutamide most effective with fewer side effects.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

The document concludes that managing PCOS involves treating symptoms and reducing long-term metabolic risks, with lifestyle changes being important.

Biotin and biotinidase are essential to prevent health issues, and deficiencies require lifelong supplementation.

Pegvaliase effectively reduces blood phenylalanine levels in most PKU patients, but requires personalized plans and good communication to manage side effects.

The rhg mutation in mice affects the Oat gene, causing hair growth issues and other symptoms.

Both metformin and pioglitazone improve PCOS symptoms, but pioglitazone is a good alternative for those who can't take metformin.

Imaging helps detect adrenal gland issues and monitor treatment in congenital adrenal hyperplasia, and can identify tumors affecting fertility.

People with hypothyroidism and hair loss often have more hair and scalp issues than those without thyroid problems.

Ovarian hyperthecosis should be considered in young women with severe male-like symptoms and can be managed with hormone treatments.

Dutasteride more effectively lowers DHT levels in men with enlarged prostates than finasteride.

GnRH analogue can help diagnose ovarian causes of high testosterone in postmenopausal women when scans don't show the cause.

Postmenopausal hyperandrogenism, a condition with symptoms like increased hair growth and acne, is usually caused by PCOS but can also be due to other factors. It's diagnosed by checking testosterone levels and treated either by removing the adrenal tumor or through antiandrogen therapy.

Western diet may cause male pattern baldness; low glycemic diet with magnesium could help.

Diabetes often causes various skin problems and complications.

A yeast-based test can detect the steroid methyltestosterone in urine longer than traditional methods.

A postmenopausal woman's masculine symptoms improved after surgery for a hormone-producing ovarian tumor.

Biotin supplements are unnecessary for most people but may help with certain conditions like biotin deficiency, brittle nails, and some hair loss.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Minoxidil breakdown varies by enzymes, affecting hair loss treatment effectiveness.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.