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The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

The Multi-Organ-Chip improves the growth and quality of skin and hair in the lab, potentially replacing animal testing.

Laser hair removal is the most requested cosmetic procedure and has become a scientifically-based treatment suitable for all skin types.

Fungi-produced compounds can change plant root growth.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Experts recommend thorough medical, sexual, and psychosocial assessments for women's sexual dysfunctions, and suggest individualized treatment plans with regular check-ups. They also mention potential use of estrogen and androgen therapy, but with caution due to safety concerns.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.

Some vitamins and minerals like vitamin D and iron can help with certain types of hair loss, but more research is needed for others.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.

Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.

New micelle solutions greatly improve skin delivery of certain antifungal drugs.

Correct skin biopsy techniques are crucial to avoid misdiagnosis of skin diseases.

The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.

The definition of Polycystic Ovary Syndrome may change with new research, and careful screening is key for managing the condition.

Wool follicles are complex, involving interactions between different cell types and structures.

Exosomes from dermal papilla cells can help grow hair and might treat hair loss.

Treatments for melanin disorders exist, but more effective options needed.

Skin grafting can help repigment vitiligo, but it's less effective for widespread cases due to the Koebner phenomenon.

A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.

An imbalanced gut and lack of biotin can cause hair loss in mice.

The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.

White lupin uses specific genes to grow root hairs and access phosphorus when it's scarce.

Procyanidin compounds from grape seeds were found to significantly increase mouse hair growth.