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Isotretinoin therapy for acne can cause many reversible side effects, mainly mild skin conditions, and patient understanding of these effects can improve treatment adherence.

Minoxidil, a hair loss treatment, works better and has fewer side effects when put into tiny particles called transethosomes, especially those containing oleic acid.

Ceramide-rich liposomes can effectively repair and strengthen damaged hair.

Tiny particles called anionic squarticles can effectively remove a common antidepressant from the body after an overdose.

The skin has multiple layers and cells, serves as a protective barrier, helps regulate temperature, enables sensation, affects appearance, and is involved in vitamin D synthesis.

The Ysc84/SH3yl1 protein family is important for cell movement and the process of taking in materials by interacting with actin and cell membranes.

Sebaceous glands in the skin play a key role in absorbing the antiandrogen drug RU 58841, especially when it's encapsulated in liposomes.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Cathepsin L is essential for normal hair growth and development.

Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.

Understanding skin structure and development helps diagnose and treat skin disorders.

A tough membrane between the outer and inner layers of human hair protects it from damage.

The skin protects the body, regulates temperature, senses touch, and makes vitamin D.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

Wound dressing absorbs fluid, regenerates hair follicles, and heals skin burns.

Surface-modified nanostructured lipid carriers can improve hair growth treatments.

Human hair structure varies by ethnicity, and certain treatments can improve hair condition and appearance.

Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.

The nanofibers with two growth factors improved wound healing by supporting structure, preventing infection, and aiding tissue growth.

The interdigital gland in crossbred sheep is similar to skin and has specialized structures for secretion.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Wool follicles are complex, involving interactions between different cell types and structures.

Keratin 79 marks a new group of cells that are key for creating and repairing the hair follicle's structure.

Activating β-catenin in mammary cells leads to changes that cause early-stage abnormal growths similar to skin structures.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Current and future treatments for alopecia areata focus on immunosuppression, immunomodulation, and protecting hair follicles.

Genetically-altered adult stem cells can help in wound healing and are becoming crucial in regenerative medicine and drug design.

Nanotechnology improves cosmetics' effectiveness and safety.