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Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Particles around 100 nm can penetrate and stay in hair follicles without passing through healthy skin, making them safe for use in topical products and useful for targeted drug delivery.

Children with atopic dermatitis often have sleep problems, affecting their growth and behavior.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

White lupin uses specific genes to grow root hairs and access phosphorus when it's scarce.

Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.

The circadian clock influences the behavior and regeneration of stem cells in the body.

RTA 408 cream protects mice from radiation skin damage.

Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.

Prostaglandin D₂ might be targeted for new male pattern baldness treatments.

Stem cells help repair tissue mainly by releasing beneficial substances, not by replacing damaged cells.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Certain microRNAs in the fluid around eggs are linked to Polycystic Ovary Syndrome and may help diagnose it.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Panax ginseng is generally safe with mild side effects and may have health benefits, but more research is needed.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

Weight loss and metformin don't significantly change vaspin levels in women with PCOS.

Researchers isolated a new type of stem cell from mouse skin that can renew itself and turn into multiple cell types.

pH, calcium, and reactive oxygen species regulate plant cell growth, with key roles for NADPH oxidases and plasma membrane H+-ATPases.

An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.

New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.