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The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

The Rotterdam Study aims to understand various diseases in older adults.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

Fat cells in the skin help start healing and form important repair cells after injury.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Liposomes could improve how skin care products work but are costly and not very stable.

Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.

Scientists created stem cells that can grow hair and skin.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.

The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.

Mutant mice help researchers understand hair growth and related genetic factors.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

Mannosylerythritol lipids are good for skin and hair care products.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

Human hair follicle stem cells can turn into multiple cell types but lose some of this ability after being grown in the lab for a long time.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

New LPA receptors (LPA4, LPA5, LPA6) have diverse roles in the body.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

Eclipta alba has many health benefits and contains compounds with potential for drug development.

Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.

Changes in skin microbes play a role in some skin diseases and could lead to new treatments.

Scientists created a gel with nanoparticles to deliver medicine to hair follicles effectively.

Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.