273 citations
,
May 2017 in “The Lancet” This review discusses the diagnosis and management of severe cutaneous adverse reactions to drugs and provides guidance for physicians to improve patient outcomes, but it reports no new clinical results.
229 citations
,
August 2002 in “Experimental Gerontology” This paper discusses key mechanisms of androgen metabolism in androgenetic alopecia and reports the effectiveness of treatments like oral finasteride and topical minoxidil, highlighting the limited success rate due to factors like follicular inflammation.
226 citations
,
September 2001 in “Journal of The American Academy of Dermatology” Hair loss in women is genetic, diagnosed by examination and biopsy, and treated with minoxidil, finasteride, or transplantation.
183 citations
,
January 2018 in “Cosmetics” This review discusses side effects and allergy contact dermatitis caused by essential oils in cosmetic products and reports no new clinical results.
158 citations
,
July 1993 in “The Journal of Pediatrics” This study observed that omeprazole was highly effective in reducing symptoms and esophagitis in children with severe esophagitis unresponsive to other treatments, though its long-term safety regarding elevated gastrin levels remains uncertain.
150 citations
,
October 2010 in “The American Journal of Pathology” This review discusses the pathogenesis and challenges in treating primary cicatricial alopecia, highlighting the need to understand immune protection collapse in hair follicle stem cells; it reports no new clinical results.
149 citations
,
July 2002 in “Dermatologic clinics” This review discusses the pathogenesis, clinical presentation, diagnosis, and treatment of cutaneous lupus erythematosus, reporting no new clinical findings.
148 citations
,
December 2018 in “Journal of autoimmunity” This review discusses genetic and environmental factors contributing to autoimmunity in alopecia areata and reports no new clinical findings, emphasizing the need for further study on its aetiology and pathophysiology.
148 citations
,
February 2005 in “Autoimmunity Reviews” This article discusses the distinct skin findings associated with lupus erythematosus, noting that some are specific to lupus while others are nonspecific and occur with various diseases; it reports no new results.
144 citations
,
September 2006 in “Clinics in Dermatology” This article outlines manifestations of systemic lupus erythematosus, noting rapid joint symptom improvement with corticosteroids and antimalarial drug responsiveness for skin symptoms, and links anti-Ro with photosensitive rash and subacute lupus.
128 citations
,
September 2011 in “British Journal of Dermatology” Obesity is linked to various skin problems and may increase the risk of skin cancer.
123 citations
,
August 2005 in “Journal of the European Academy of Dermatology and Venereology” In this study, the researchers observed that treatment with intralesional and topical corticosteroids, finasteride, and minoxidil may stop the progression of frontal fibrosing alopecia in postmenopausal and premenopausal women.
106 citations
,
December 2015 in “Journal of The American Academy of Dermatology” This article reviews common pitfalls in biopsy site selection and technique that can lead to misdiagnosis of various skin conditions, highlighting the importance of proper biopsy practices for improving diagnostic accuracy.
98 citations
,
January 2013 in “Journal of The American Academy of Dermatology” This study reported that while various treatments for frontal fibrosing alopecia showed limited effectiveness, dutasteride most effectively stabilized the condition among patients at Duke University.
95 citations
,
November 2016 in “Journal of The American Academy of Dermatology” This article reviews primary cicatricial alopecias, focusing on lymphocytic forms such as chronic cutaneous lupus erythematosus, according to a classification by the North American Hair Research Society, and reports no new clinical results.
90 citations
,
July 2008 in “Dermatologic therapy” This article reviews lichen planopilaris, a chronic scarring alopecia, and explores recent treatment developments, but it reports no new clinical results.
90 citations
,
June 2006 in “The American Journal of Dermatopathology” This review outlines the classification, histopathologic presentation, and pathogenetic concepts of scarring and nonscarring alopecias, reporting no new clinical results and emphasizing the need for clinicopathologic correlation.
87 citations
,
December 2016 in “British journal of dermatology/British journal of dermatology, Supplement” This study describes and characterizes four cases of alopecia areata induced by immune checkpoint inhibitor therapy in cancer patients, highlighting the importance of recognizing and managing these hair-related adverse events.
80 citations
,
April 2018 in “Trends in Molecular Medicine” This review discusses the roles of interferon-γ and PPAR-γ-mediated signalling in scarring alopecia, suggesting these pathways as potential therapeutic targets, but it reports no new empirical results.
76 citations
,
July 2011 in “Clinical, Cosmetic and Investigational Dermatology” This review discusses clinical methods for diagnosing alopecia and examines current treatments for both cicatricial and noncicatricial forms but provides no new clinical results.
72 citations
,
July 2008 in “Dermatologic Therapy” This article reviews central centrifugal cicatricial alopecia in African-descent females, discussing possible causes, associated styling habits, and potential treatments, but reports no new clinical findings; the authors call for further research.
68 citations
,
September 2003 in “British Journal of Dermatology” This study found that in thin cutaneous melanomas, tumor regression is associated with a higher risk of sentinel lymph node involvement.
65 citations
,
January 2009 in “Pediatric Dermatology” In this retrospective study at a New Delhi children's hospital, the authors found that pediatric skin diseases were most commonly infections and infestations, with bacterial infections and scabies leading, followed by eczemas.
64 citations
,
January 2004 in “American journal of clinical dermatology” This review describes various types of folliculitis based on their causes, clinical manifestations, and treatments, but reports no new clinical results.
62 citations
,
March 2012 in “Journal of the European Academy of Dermatology and Venereology” This study found that dermoscopy-guided scalp biopsies provided a definitive pathological diagnosis in 95% of patients with cicatricial alopecia.
60 citations
,
September 2013 in “Alimentary Pharmacology & Therapeutics” This review discusses the dermatological adverse events from immunosuppressive and anti-TNF therapy in IBD, finding increased risks of non-melanoma skin cancer and other skin conditions, and recommends regular cancer screening.
59 citations
,
June 2022 in “Frontiers in medicine” This review discusses the complex causes and treatment challenges of chronic inflammatory skin diseases, emphasizing the need for biomarkers to predict treatment responses; it reports no new clinical results.
57 citations
,
August 2003 in “British Journal of Dermatology” This study found that daily use of 1% pyrithione zinc shampoo modestly improved hair growth over 26 weeks, although these effects were less than those of 5% minoxidil.
56 citations
,
January 2019 in “Skin appendage disorders” In this multicenter study, androgenetic alopecia was the most common type of alopecia among both men and women attending specialty hair clinics on four continents.
51 citations
,
March 2014 in “Nature Communications” This study suggests that activating retinoic acid signalling can inhibit Wnt signalling and induce regression in certain skin tumors, providing potential therapeutic strategies for tumor regression.