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Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.

The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

Cyclosporine A may help treat hair loss by blocking a protein that inhibits hair growth.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Stress can worsen skin conditions by affecting hormone levels and immune response.

Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.

Hirsutism is excessive hair growth in women often caused by polycystic ovarian syndrome, and identifying the cause is important for managing associated health risks.

Androgens cause skin issues like acne and hair growth in women, often due to PCOS, and can be treated with medication and lifestyle changes.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Women with acromegaly often have irregular periods due to hormone imbalances and growth hormone effects.

Mood stabilizers like lithium and anticonvulsants have side effects that can lead to patients stopping their medication, and managing these effects is important for treatment adherence.

Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

Brain-Derived Neurotrophic Factor (BDNF) slows down hair growth and promotes hair follicle regression.

Condensed nanofat with fat grafts effectively improves atrophic facial scars.

Improving insulin sensitivity and weight loss can help manage polycystic ovary syndrome (PCOS).

PCOS symptoms change with age; younger women have higher androgen levels and less metabolic issues, while older women face more metabolic challenges despite milder PCOS symptoms.

The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.

PCOS is often linked to insulin resistance and obesity, and weight loss can improve symptoms.

Certain fungi and bacteria help orchid seeds germinate and plants grow better.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.

The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.