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330-360 / 1000+ resultsresearch DUTASTERIDA ORAL VERSUS FINASTERIDA ORAL NO TRATAMENTO DA ALOPECIA ANDROGENÉTICA MASCULINA: META-ANÁLISE DE EFICÁCIA E PERFIL DE EFEITOS ADVERSOS SEXUAIS
In this systematic review, dutasteride may be more effective than finasteride for hair growth in men with androgenetic alopecia, but the comparative magnitude of this effect is highly uncertain.
research Risk of age-related macular degeneration in men receiving 5α-reductase inhibitors: a population-based cohort study
In this retrospective, population-based cohort study, researchers found no significant difference in age-related macular degeneration incidence between BPH patients using 5α-reductase inhibitors and those on tamsulosin, but observed a slight increased risk with dutasteride compared to finasteride.
research Finasteride
research Risk of Type 2 Diabetes Mellitus in New Users of 5-Alpha Reductase Inhibitors: A Nationwide Historical Cohort Study
Finasteride and dutasteride have little effect on Type 2 Diabetes risk.
research Effect of 5α-Reductase Inhibitors on Sexual Function: A Meta-Analysis and Systematic Review of Randomized Controlled Trials
This study concluded that 5α-reductase inhibitors were linked to increased sexual dysfunction in men with benign prostatic hyperplasia, but not in men with androgenetic alopecia.
research Key Clinical Trials in BPH
This review discusses various treatments for benign prostatic hyperplasia, comparing medications like finasteride and terazosin, as well as surgical and placebo options, without presenting new clinical findings.
research Dutasteride, finasteride: no increased risk of ED
Dutasteride and finasteride don't raise erectile dysfunction risk.
research Food Administration and Not Genetic Variants Causes Pharmacokinetic Variability of Tadalafil and Finasteride
In this study, researchers investigated genetic variants in pharmacogenes affecting tadalafil and finasteride pharmacokinetics, finding fed volunteers had higher drug exposure than fasting individuals, but genetic variation did not significantly impact pharmacokinetics after correcting for multiple comparisons.
research Liquid chromatographic-mass spectrometric method for determination of drug content uniformity of two commonly used dermatology medications in a split-tablet dosage form
This study found that the proposed LC-MS/MS method accurately quantified the drug content in split tablets of finasteride and terbinafine, revealing significant variability and suggesting that non-scored tablets should not be split.
research RP-HPLC-Based Stability-Indicating Analytical Method for Concurrent Determination of Finasteride and Tadalafil: Development and Validation
In this study, researchers developed a reliable HPLC method to simultaneously estimate Finasteride and Tadalafil in marketed formulations, showing precise, linear results with confirmed degradation susceptibility under certain stress conditions.
research FORMULATION AND EVALUATION OF CONTROLLED RELEASE MATRIX TABLETS OF FINASTERIDE
In this study, the release rate of Finasteride from Eudragit matrix tablets was found to be significantly influenced by the drug/Eudragit ratio and polymer viscosity, with formulation F9 being the most effective.
research Determination of finasteride in human plasma by LC-MS and its pharmacokinetics
This study found that domestic finasteride tablets are bioequivalent to reference tablets, showing similar pharmacokinetic parameters and relative bioavailability.
research Market Analysis of 5α-Reductase Inhibitor
This study concluded that the market for 5α-reductase inhibitors, including finasteride, epristeride, and dutasteride, is expected to grow with promising prospects.
research Finasteride
Finasteride helps hair growth and prostate issues but may cause sexual side effects and increase tumor risk.
research Medical Therapies for Treatment of BPH: Special Considerations in Elderly Men
Tailored treatment is crucial for elderly men with BPH due to potential risks and benefits of medications.
research A pharmacovigilance study of drug‐reduced male semen quality based on the Food and Drug Administration adverse event reporting system database
Using data from the FDA's adverse event reporting system, this study identified 59 drugs linked to reduced male semen quality, with finasteride, dutasteride, and tamsulosin among the most frequently reported.
research Prospective randomized study of sexual function in men taking dutasteride for the treatment of androgenetic alopecia
In a randomized study, men treated with dutasteride for androgenetic alopecia experienced sexual adverse events at twice the rate of those on placebo during 24 weeks, but these events were mild, moderate, and resolved after treatment.
research Non-Steroidal Modulation of the 5-Alpha Reductase Axis: A Dual Therapeutic Strategy for Prostatic Chemoprevention and Androgenetic Alopecia
This study reports the discovery of LX-38, a new high-affinity non-steroidal antagonist that could provide the therapeutic benefits of current BPH and AGA treatments without the hormonal side effects, utilizing a distinct "Orthogonal T-Stacking" scaffold for binding.
research AB032. Development of new treatment modality for male infertility by using phytopharmaceuticals
This study explored the effects of MOTILIPERM on infertility in a rat model with varicocele and oxidative stress, reporting its potential therapeutic efficacy.
research Finasteride had fewer sexual side effects compared to dutasteride in men with BPH
Finasteride causes fewer sexual side effects than dutasteride in men with BPH.
research Long-term treatment with finasteride: sexual adverse events and fracture rates
Finasteride can cause sexual side effects like decreased libido and erectile dysfunction.
research Variability of Retail Pricing of Generic Urologic Medications in a Major US Metropolitan Area
This study found that independent pharmacies in the St. Louis area offer significantly lower prices for tamsulosin and oxybutynin ER compared to chain pharmacies, while zip-code and median income show no pricing correlation.
research Studies on the pharmacokinetics and bioquivalence of domestic finasteride tablet in healthy volunteers
This study concluded that domestic and imported finasteride tablets are bioequivalent, showing no significant differences in pharmacokinetic parameters among healthy volunteers.
research 5α‐Reductase Inhibitors
This review discusses 5-alpha reductase inhibitors, highlighting their long-term efficacy and tolerability in treating benign prostate hyperplasia, while also noting sexual dysfunction as a common adverse effect.
research Inhibitors of 5α-Reductase in the Treatment of Benign Prostatic Hyperplasia
This review discusses the use of 5α-reductase inhibitors in treating benign prostatic hyperplasia, highlighting their long-term effectiveness and benefits when combined with α1-adrenergic antagonists; it reports no new clinical results.
research The Long-Term Effect of Doxazosin, Finasteride, and Combination Therapy on the Clinical Progression of Benign Prostatic Hyperplasia
Combination therapy of doxazosin and finasteride safely and effectively reduces benign prostatic hyperplasia progression risk.
research Abstracts from the current global literature: Finasteride and sexual dysfunction
Finasteride, a hair loss drug, can cause sexual side effects like erectile dysfunction in 2.1%-3.8% of users, but these usually go away with time or if the drug is stopped. Despite this, its impact on sexual function is minimal for most men.
research Determination of Finasteride in Human Plasma by HPLC-MS and Study on the Bioequivalence of Domestic and Import Finasteride Tablets
This study concluded that domestic and imported finasteride tablets are bioequivalent, with no significant differences in their pharmacokinetics among healthy volunteers.
research Incomplete Recovery of Erectile Function in Rat after Discontinuation of Dual 5‐Alpha Reductase Inhibitor Therapy
In this study using a rat model, discontinuing dutasteride improved some relaxant responses but did not fully restore erectile function, indicating a potential time-dependent detriment of the drug.