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The enzyme Rand protease works well for leather dehairing and its stability is important, with Leu75 playing a key role.

A boy with Pachyonychia congenita has a confirmed gene mutation, highlighting the need for a local genetic database in India.

A boy's skin fragility and sparse hair were caused by a genetic mutation affecting skin cell adhesion.

Severe alopecia areata involves higher levels of certain immune cells, which can be normalized with betamethasone.

The compound 4c showed strong potential as an anticancer agent.

A man with testotoxicosis was fertile despite low FSH levels, suggesting high testosterone may allow sperm production without FSH.

A compound from Calophyllum inophyllum L. leaf may help treat non-small cell lung cancer.

Three compounds from Dadap leaves may help treat hair loss.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

FOXN1 gene variants cause low T cells and immune issues from birth.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

The skin's basement membrane has specialized structures and molecules for different tissue interactions, important for hair growth and attachment.

Toxic Epidermal Necrolysis is a rare, serious skin condition that can affect anyone, is more common in women, and may be linked to genetics, with a 20% mortality rate mainly due to sepsis.

FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.

A specific gene change plus an additional mutation in the same gene cause hereditary trichilemmal cysts.

Whale genes show changes that help them live in water, like less hair and better flippers.

Some new isatin compounds could be strong cancer-fighting drugs because they fit well in cancer-related proteins and have good drug-like properties.

Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.

Analog 23 is a promising compound for prostate cancer treatment.

A patient with Werner syndrome showed a range of aging-like symptoms and metabolic issues, underscoring the need for early detection and treatment.

The proteins transthyretin and megalin are more present in the growth phase of hair, suggesting they might affect hair health and growth.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

KATP channels are important for energy balance and are targeted by drugs for diabetes, hypoglycemia, hypertension, and hair loss.

Certain Dibenzo derivatives may help treat prostate cancer.

Watercress oil may promote hair growth by activating specific receptors.

Mutations in the enzyme don't significantly change how it binds to its specific substances.

Compounds from the Sansevieria trifasciata plant might be effective for treating hair loss.

The skin's basement membrane is specially designed to support different types of connections between skin layers and hair follicles.

Molecular diagnostics help identify genetic defects causing endocrine diseases, improving diagnosis and treatment options.

A new MBTPS2 gene variant disrupts fat metabolism and collagen production, causing Osteogenesis imperfecta.