Molecular Determinants for the Chemical Activation of the Warmth-Sensitive TRPV3 Channel by the Natural Monoterpenoid Carvacrol
February 2022
in “
Journal of Biological Chemistry
”
Studysummary This study found that carvacrol activates the TRPV3 ion channel by binding to a specific pocket formed by the S2-S3 linker, providing insight into its role in skin sensitization and potential for designing specific modulators.
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