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Different types of stem cells in the skin contribute to the variety of melanoma forms.

A new treatment using AGED to modulate PPAR-γ shows promise for treating scarring hair loss by protecting and repairing hair follicle cells.

Cholecystokinin may help reduce skin inflammation in psoriasis.

Deep phenotyping helps distinguish between xeroderma pigmentosum and trichothiodystrophy, aiding in diagnosis and treatment.

Hair pattern in androgenetic alopecia overlaps with scalp and bone demarcations, with distinct gene profiles affecting susceptibility.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

Fat-related cells are important for initiating hair growth.

Turning white fat into brown-like fat could help fight obesity and type 2 diabetes.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Stem cell-derived conditioned medium shows promise for treating various medical conditions but requires standardized production and further validation.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Fat cells help recruit healing cells and build skin structure during wound healing.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Stem cell niches support, regulate, and coordinate stem cell functions.

Women with PCOS face higher risks of diabetes and heart disease, and these risks increase with obesity.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.