April 2026 in “International Journal of Research in Dermatology” This meta-analysis found that laser-based therapies showed promising clinical benefits in treating scarring alopecias, such as disease stabilization and symptom improvement, but highlighted the need for high-quality randomized controlled trials due to serious risk of bias and methodological limitations in existing studies.
1 citations
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September 2025 in “Journal of Cosmetic Dermatology” This study introduces the "skinspan" framework to promote skin longevity through sun protection, topical retinoids, and antioxidants as first-line care. It suggests lasers and emerging therapies as additional options but emphasizes the need for more randomized controlled trials to solidify the evidence base.
March 2026 in “Journal of the American Academy of Dermatology” This clinical review evaluates current evidence on various adjunctive therapies for androgenetic alopecia, highlighting modest benefits for some interventions but emphasizing significant gaps and the need for rigorous, high-quality research to guide effective management strategies.
21 citations
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May 2016 in “The Cochrane library” This review found that while topical minoxidil is effective for treating female pattern hair loss, finasteride showed no more effectiveness than placebo, and low-level laser therapy increased hair count but with inconsistent results.
March 2026 in “Healthcare” In this study conducted among adult dermatology clinic attendees in Saudi Arabia, laser hair removal-related anxiety was generally low, but misconceptions were common; increased knowledge was linked to reduced anxiety, suggesting educational interventions could improve informed decision-making.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, researchers created a comprehensive transcriptome map of human hair follicle compartments, identifying compartment-specific genes and providing a resource for potential therapeutic interventions.
3 citations
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November 2021 in “Clinical, Cosmetic and Investigational Dermatology” This review evaluated existing studies on platelet-rich plasma for facial rejuvenation and found limited clinical evidence supporting its effectiveness, suggesting that more research is needed to establish its utility.
1 citations
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September 2024 in “Benha Journal of Applied Sciences” This review provides an overview of androgenetic alopecia, detailing its causes, diagnostic methods, and current treatments, noting that combination therapies show promise but newer options like cell-based treatments require more research.
February 2026 in “American Journal of Clinical Dermatology” This source discusses how radiotherapy-induced skin fibrosis, a chronic side effect affecting cancer survivors' quality of life, is driven by ongoing inflammation and fibroblast activity, and emphasizes the need for comprehensive dermatologic management and better diagnostic tools.
June 2026 in “Facial Plastic Surgery” This review concluded that non-surgical hair restoration methods, such as pharmacologic and regenerative therapies, are important for delaying or supplementing surgical treatments when used properly.
40 citations
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October 2012 in “British Journal of Dermatology” This review assessed available treatments for female pattern hair loss and found that minoxidil improved hair regrowth compared to placebo, though high-quality evidence was limited for other interventions.
January 2025 in “Advances in Clinical Medicine” This source highlights that fractional CO2 laser, as a minimally invasive technology, shows significant benefits in treating various skin and mucosal conditions by improving therapeutic outcomes, shortening recovery times, and enhancing precise personalized interventions through emerging technologies like AI and biomarker monitoring.
30 citations
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February 2016 in “British journal of dermatology/British journal of dermatology, Supplement” This review found moderate to very low-quality evidence that spironolactone, flutamide, and cyproterone acetate combined with oral contraceptives may reduce hirsutism more effectively than placebo or metformin, though results vary among other treatments.
33 citations
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April 2015 in “Cochrane library” This review examined various treatments for hirsutism and found low to very low quality evidence suggesting that flutamide and spironolactone may help reduce hair growth, while metformin was ineffective.
4 citations
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October 2025 in “Journal of Cosmetic Dermatology” This study reported severe and persistent skin reactions, including inflammation and scarring, after intradermal injections of unregulated exosome-based products, highlighting potential risks in aesthetic dermatology.
August 2025 in “Dermatological Reviews” This review reports that stem cell-based therapies, natural oils, and low-level laser therapy may offer promising and safe alternative treatments for alopecia, although further standardized trials are needed for confirmation.
6 citations
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August 2023 in “Fertility and Sterility” This review details the 2023 International Guideline update for assessing and managing polycystic ovary syndrome, which provides evidence-based recommendations to improve care and patient outcomes but notes the remaining low to moderate quality of evidence.
December 2024 in “Benha Journal of Applied Sciences” This study reports that combination therapies, including surgical and various medical treatments, show promise for managing androgenetic alopecia, though further research is necessary to confirm the safety and effectiveness of emerging therapies.
3 citations
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January 2008 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” This article reviews factors influencing hidradenitis suppurativa, its clinical diagnosis, and the diverse management approaches but presents no new clinical findings.
June 2025 in “British Journal of Dermatology” This review highlights that acne keloidalis nuchae notably affects men with afro-textured hair and results in scarring and hair loss, underscoring the need for improved diagnosis and treatment strategies due to its significant psychosocial impact and high recurrence rates following current therapies.
December 2025 in “IP Indian Journal of Clinical and Experimental Dermatology” This review reports that the treatment of androgenetic alopecia is shifting from single therapies to personalized, multimodal approaches incorporating both traditional and emerging pharmacologics, regenerative strategies, nutraceuticals, cosmeceuticals, and device-based interventions, with combination regimens showing improved outcomes.
May 2023 in “Elsevier eBooks” This study found that low-level laser/light therapy is effective and safe for treating mild to moderate androgenetic alopecia in individuals with certain skin types, especially when combined with other treatments, although further research is needed to refine protocols and verify long-term outcomes.
May 2014 in “Journal of Aesthetic Nursing” This summary reflects on the success of the Health Education England stakeholder summit on non-surgical cosmetic interventions and outlines future training plans without reporting new research results.
In this case report, an African American male with signs of acne keloidalis nuchae highlights the condition's chronic nature and need for early intervention to minimize permanent scarring and its psychosocial impact.
46 citations
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October 2012 in “Dermatologic Clinics” This review discusses treatment options for female pattern hair loss, emphasizing the importance of early intervention and the benefits of combined therapies, but reports no new clinical results.
June 2024 in “Bangladesh Journal of Medicine” This study offers a comprehensive overview of alopecia, detailing its various types, diagnostic approaches, and treatment options, including updated medical and procedural interventions such as Tofacitinib, PRP therapy, and microneedling, among others.
69 citations
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April 2010 in “British Journal of Dermatology” This study found a significant association between androgenetic alopecia and metabolic syndrome, highlighting high-density lipoprotein cholesterol as a particularly important factor.
373 citations
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September 2009 in “Obstetrics & Gynecology” This review examines the best available evidence for diagnosing and managing PCOS but reports no new clinical results.
54 citations
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June 2006 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” This review discusses the management of hirsutism and acne in women with polycystic ovary syndrome, highlighting the partial effectiveness of current treatments and suggesting a combined approach of medication and hair removal.
989 citations
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August 2007 in “The Lancet” This article reviews the clinical features, diagnostic criteria, and possible genetic and environmental influences of polycystic ovary syndrome but provides no new research findings.