research A Guide to the Use of Bioassays in Exploration of Natural Resources
Bioassays help find useful compounds in nature for making medicines, supplements, and cosmetics.
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research Preclinical Evidence Supporting Selective Inhibition of Tyrosine Kinase 2-Dependent, IL-12-Mediated Signaling as a Novel Strategy for Alopecia Areata Management
Blocking TYK2 might be a new way to treat hair loss from alopecia areata.
research Scarring Alopecia Is Driven by the Collapse of EGFR-Protected JAK-STAT1-Sensitive Stem Cell Immune Privilege
Cancer treatment drugs can cause permanent hair loss by damaging hair follicle stem cells, but a specific inhibitor might reverse this effect.
research Clinical and Molecular Features in a Cohort of Middle Eastern Patients With Epidermolysis Bullosa
Middle Eastern patients with epidermolysis bullosa show specific genetic mutations linked to different types of the disease.
research Efficacy of Platelet-Rich Plasma for the Treatment of Androgenetic Alopecia
Platelet-rich plasma treatment is effective for increasing hair thickness and works well for hair density in men with androgenetic alopecia.
research Effect of a Keratin Coupling Agent on the Mechanical Properties of a Bovine Hair-Thermoplastic Starch Composite
Adding keratin to a mix of cow hair and plant-based plastic makes it stronger.
research The Rho GTPase Exchange Factor Vav2 Promotes Extensive Age-Dependent Rewiring of the Hair Follicle Stem Cell Transcriptome
Vav2 changes how hair follicle stem cells' genes work as they age, which might improve regeneration but also raise cancer risk.
research Hairdressing Practices and Alopecia Among Women Aged 15 to 45 in Bamako
Certain hair styling methods, like weaving and straightening, are a main cause of hair loss in women from Bamako.
research Clinical Case of Alopecia Totalis in Pediatric Practice
An 11-year-old child with total hair loss may have a genetic autoimmune disease, and the outlook for hair regrowth is not good.
research A Randomized Double-Blind Placebo-Controlled Clinical Trial to Evaluate the Effect of an Annurca Apple Supplement Formula in Androgenic Alopecia
The Annurca apple supplement significantly improved hair growth in people with hair loss.
research The Role of Neurorehabilitation in Post-COVID-19 Syndrome
Tailored neurorehabilitation programs improve life quality for post-COVID-19 patients.
research Exosomes/EVs: Advanced Cell-Based Therapies for Hair Loss: A Comprehensive Systematic Review
research Ovarian Hyperthecosis as a Cause of Hypersexualization in a Post-Menopausal Female
Ovarian Hyperthecosis caused hypersexuality in an older woman and was successfully treated with surgery.
research HPV8 E6 Induced STAT3 Activation Leads to Hair Follicle Junctional Zone Keratinocyte Stem Cell Proliferation and Expansion in Actinic Keratoses
HPV8 causes hair follicle stem cells to grow, leading to skin lesions.
research Pain Digital Biomarker Detection by Epidermal Biopotential Flexible Sensor and AI-Based System
A new pain-measuring system using sensors and AI can effectively detect pain in mice, which may help assess pain in humans and develop treatments.
research Enzymatic Digestion of Scalp Hair Follicle Bulge Yields More Stem Keratinocytes Than Explant Isolation
Using enzymes to break down scalp hair follicles gets more stem cells for skin and hair growth than the old method.
research Deletion of Hoxc13 in Frogs Reveals Key Steps in the Molecular Evolution of Cornified Skin Appendages
Deleting the Hoxc13 gene in frogs shows its crucial role in developing skin structures similar to hair.
research Effects of a New Recombinant Human Collagen on Skin Aging
The new recombinant human collagen can help slow skin aging and repair skin, while also controlling inflammation.
research Phenotypic Heterogeneity of Epidermolysis Bullosa Associated With the Recurrent Pathogenic Variant p.(Arg2000Trp) in Plectin
The specific skin disease variant p.(Arg2000Trp) in plectin can cause a wide range of symptoms, which should be considered when diagnosing patients.
research Terminalia Chebula Fruit Extract From PSR Technology Demonstrates Strong Anti-Aging and Antioxidant Properties
Terminalia chebula fruit extract has strong anti-aging and antioxidant effects.
research Uncoupling Desmosomal Cadherin Adhesion Activates Quiescent Hair Follicle Stem Cells and Orchestrates Self-Organized Regeneration Through Outside-In Signaling
Disrupting a specific protein's function in hair follicle stem cells triggers their activation and a self-healing process.
research Basal Keratinocytes Exhibit Age-Related Epigenetic and Transcriptomic Alterations Resulting in an Altered Metabolic Profile
Aging changes skin cells, leading to different DNA methylation and gene activity, affecting cell metabolism and aging signs.
research Response to Ritlecitinib Treatment Based on Salt Improvement Scores in Patients With Alopecia Areata: Post Hoc Analysis of the Allegro Phase 2b/3 Study
Ritlecitinib significantly improves scalp hair regrowth in alopecia areata patients over time.
research Autophagy Controls the Protein Composition of Hair Shafts
Autophagy is important for determining the protein makeup of hair.
research Spectrum Changes of Pediatric Dermatological Disorders Before and During the COVID-19 Pandemic in China: A Single National Center for Children's Health Experience
During the COVID-19 pandemic in China, skin conditions like eczema and warts increased among children, while respiratory-transmitted skin infections decreased, partly due to mask-wearing.
research Epidermal Growth Factor Receptor Protects From Immune Privilege Collapse and Scarring Hair Follicle Destruction
Blocking EGFR can lead to hair loss due to inflammation and stem cell damage.
research Comorbid Conditions Associated With Alopecia Areata: A Systematic Review and Update
People with Alopecia Areata are more likely to have certain health issues like ulcerative colitis and type 1 diabetes, but less likely to have others like hypertension and type 2 diabetes.
research Clinical Technique and Outcomes of Platelet-Rich Plasma Application for Treatment of Androgenic and Scarring Alopecia, Acne Scarring, Melasma, and Facial Rejuvenation: A Prospective Multicenter Study
Platelet-rich plasma treatment is generally safe and effective for hair loss, acne scars, skin discoloration, and facial rejuvenation, but deeper injections are better and multiple treatments can increase risk of side effects.
research A Quantitative Study of Desquamation in the Stratum Corneum
New method measures skin cell turnover quickly and effectively, showing turnover slows with age and responds more to treatments in older skin.
research Fate Tracing of DNA-Damaged Hair Follicle Stem Cells and Their Seno-Differentiation Clearance Out of the Niche
Damaged hair follicle stem cells may leave the skin to help maintain youthfulness.