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PGD2 stops hair growth and is higher in bald men with AGA.

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

Ruxolitinib effectively regrows hair in most patients with severe hair loss.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

A patient with Alopecia Areata had complete hair regrowth after using the drug baricitinib.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Blocking JAK-STAT signaling can lead to hair growth.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

K6hf is a unique protein found only in a specific layer of hair follicles.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

Mice hair growth patterns get more complex with age and can change with events like pregnancy or injury.

Oxidative stress contributes to hair graying and loss as we age.

Fat cells in the skin help start healing and form important repair cells after injury.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.

The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.

New treatments targeting specific genes show promise for treating keratin disorders.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

A cluster of sulfur-rich hair protein genes was found on chromosome 17.