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The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.

Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.

Prostaglandin D2 blocks new hair growth after skin injury through the Gpr44 receptor.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

The document concludes that alopecia areata is an autoimmune disease without a definitive cure, but treatments like corticosteroids are commonly used.

Sub3 is essential for fungus adherence but not for skin invasion.

Low iron and vitamin D levels are linked to hair loss in women.

There is no clear recommendation for using selenium in cancer patients; it may be beneficial to correct low selenium levels before treatment.

Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.

Zinc can both inhibit and stimulate mouse hair growth, and might help recover hair after chemotherapy.

Minoxidil use in children may cause heart issues.

Biotin supplements are not proven to improve hair or nails and may interfere with medical tests.

Skin grafts are effective for chronic leg ulcers, especially autologous split-thickness grafts for venous ulcers, but more data is needed for diabetic ulcers.

Most patients treated with low-dose alpha-interferon for malignant melanoma experienced skin side effects, with hair loss being the most frequent.

Nonclassic adrenal hyperplasia is a genetic condition that can cause early puberty and fertility problems, treated with specific steroids.

Genetically modified plants could be an important source of omega-3 fats to meet global needs.

The document explains hair growth and shedding, factors affecting it, and methods to evaluate hair loss, emphasizing the importance of skin biopsy for diagnosis.

Wound dressing absorbs fluid, regenerates hair follicles, and heals skin burns.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

High testosterone to epitestosterone ratio in hair could predict male-pattern baldness.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

Female pattern hair loss diagnosed by scalp appearance, treated with combined therapies and targeted approaches.

Hair loss treatments include medications and new methods like low-level light therapy, which may work by boosting cell activity and blood flow.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

Finasteride 5 mg/day effectively treats hair loss in postmenopausal women without hyper-androgenism.

Some hair loss disorders are caused by genetic mutations affecting hair growth.

Pyrene excimer nucleic acid probes are promising for detecting biomolecules accurately with potential for biological research and drug screening.