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Women with effluvium have higher levels of certain urinary steroids, possibly due to stress and increased adrenal activity.

Copper treatments increase copper in all tissues, but brindled female mice accumulate much more copper in their kidneys without clinical effects, unlike brindled male mice where brain copper deficiency is clinically significant.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Itraconazole is potentially effective for treating invasive aspergillosis, but more research is needed.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.

Myrtle has various health benefits and potential for medicine development.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Fat cells in the skin help start healing and form important repair cells after injury.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

Trilostane effectively and safely treats dogs with pituitary-dependent hyperadrenocorticism, improving symptoms and adrenal gland size.

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

The document concludes that proper diagnosis and a combination of medical, hair-care, and surgical treatments are important for managing alopecia in black women.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

Minoxidil-loaded NLC gel shows potential for effective alopecia treatment.

Minoxidil effectively treats severe hypertension but may cause side effects, so careful monitoring is needed.

Improving skin barrier and using antifungal treatments can help manage dandruff.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

The document concludes that dandruff and seborrheic dermatitis are linked to inflammation and skin changes, and treating them with specific shampoos can reduce these issues.

New antifungal treatments for a children's scalp infection are effective and safe, but it's not decided if they will become the preferred option over the old treatment.

New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

Minoxidil promotes hair growth in women with early-stage alopecia.

Effective hair loss treatment in women requires correct diagnosis and can include medications like minoxidil, antiandrogens, and treatments for underlying conditions like PCOS.

Doxil showed some effectiveness against advanced prostate cancer but caused severe side effects at higher doses.

Most dermatologic medications are safe during pregnancy and breastfeeding, but some should be avoided due to potential risks.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.