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Diabetes changes keratin in skin and hair, affecting their health.

In this study, DOP treatment improved hair regrowth in androgenetic alopecia by altering local steroid metabolism and follicular morphology.

This study found that keratin damage in mammals and birds can result from N-homocysteinylation, reducing keratin solubility and indicating significant protein modification through genetic or nutritional disruptions in homocysteine metabolism.

Androgens don't directly affect hair cell growth or protein production.

This article reviews the role of sulfhydryl compounds, particularly cystine, in sulfur metabolism and the physiology of skin in both normal and pathological conditions, reporting no new findings.

This study found that hair follicles undergo significant molecular changes with age, notably a decline in keratins and keratin-associated proteins, which may contribute to age-related hair alterations.

This study found that measuring glycosylated keratin levels in hair can estimate the onset timing of insulin-dependent diabetes mellitus after a prolonged latent phase, but not as reliably for noninsulin-dependent diabetes due to longer latency and hair length limitations.

This study suggests that melatonin may enhance wool growth in cashmere goats by activating sulfur metabolism genes and high-sulfur protein genes, which are crucial for providing sulfur-containing amino acids needed for wool quality.

This study reports that polyphenols from Annurca apples may safely promote hair growth and protect against chemotherapy-induced alopecia without interfering with chemotherapy regimens.

This study identified mutations in the SREBF1 gene that impair SREBP1 function, potentially contributing to IFAP syndrome by affecting skin, hair, and eye development.

This study found that telogen, a resting phase of the hair follicle cycle, is characterized by dynamic gene expression, including enhanced cholesterol metabolism and immune signaling, suggesting it is an active regulatory phase despite its quiescent appearance.

This study found that Super Merino sheep have a higher wool follicle density, finer fleece, and distinct gene expression compared to Small Tail Han sheep, which may inform future breeding and genetic interventions.

This study found that differentially expressed genes in horses with white versus black coats may regulate coat color, providing insights into the genetics of skin melanin synthesis.

In this study of a TRPS type I patient, many genes related to keratin and hair development were down-regulated in balding scalp areas, providing new insights into TRPS and hair morphogenesis.

In this study, ceruloplasmin and keratin 4 were identified as markers that differentiate between growing and resting phases in cashmere goat hair follicles, with keratin 4 being a potential marker for the onset of a new hair cycle.

This study identified distinct gene expression programs in keratinocytes responsible for forming hard scales and soft interscale epidermis in chickens, revealing conserved differentiation genes similar to those in human skin.

This study identified 617 differentially expressed genes in cashmere goat hair follicles, which are involved in key biological processes and provide insights into hair follicle development.

This study suggests that lipin-1 plays a crucial role in keratinocyte differentiation by modulating protein kinase C activity through diacylglycerol levels, with implications for skin biology.

This study explored how long non-coding RNA mediates the effects of FGF5 on the hair follicle development and villus growth of Liaoning cashmere goats.

This review discusses the complex interaction between androgens and hair follicle biology, highlighting the need for a better understanding to improve hirsutism treatments, but reports no new results.

This study identified differentially expressed proteins and pathways potentially involved in wool bending in Zhongwei goats, with specific genes like COL6A1 and CRNN emerging as important candidates in this process.

This study found that epidermolysis bullosa simplex keratinocytes had impaired mitochondrial activity and more dispersed mitochondrial distribution compared to normal human keratinocytes.

Using a multi-omics analysis, this study identified key regulators like PLA2G12A, KRT79, and prostaglandin B2 that influence cashmere fineness, providing crucial data for understanding the molecular mechanisms behind this trait in Liaoning cashmere goats.

Metabolic disorders can cause hair structure defects and growth issues, but amino acid levels in hair remain normal.

This study found that a solution containing 0.5% Camellia japonica placenta extract increased scalp moisture and reduced sebum content, dead keratin, and erythema in adult females, suggesting potential as a scalp treatment.

This study found that Annurca apple polyphenolic extracts reprogram hair follicle metabolism in mice, enhancing mitochondrial activity and keratin production while inhibiting some metabolic pathways.

This study visualized mitochondrial metabolism in cultured bovine hair follicles and plucked human hairs, finding that ROS and mitochondrial polarization correlate in specific hair follicle regions, particularly near keratin deposition sites.

In this study, researchers found that a high-fat diet in mice induced downregulation of certain Krtap genes in the tongue, which may be linked to structural issues or oral cancer risk, highlighting a potential connection between oral health and systemic diseases like metabolic syndrome.

This article explores how various nutrients and metabolic processes impact wool and hair follicle function in animals but reports no new experimental findings.

Pili annulati is caused by a protein metabolism disorder affecting hair structure.