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Finasteride treatment lowers urine androgen and prostaglandin levels, making them potential markers for effectiveness.

Topical spironolactone effectively treats hair loss in women.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

COVID-19 leaves 80% of patients with long-term symptoms like fatigue and headaches.

Off-pump heart surgery reduces complications without affecting survival rates compared to on-pump surgery.

Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.

Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

A mother's diet at conception can cause lasting genetic changes in her child.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

The guidelines suggest lifestyle changes, diet adjustments, and personalized medication to manage dyslipidemia and reduce heart disease risk.

DNA profiling in forensics has improved, but predicting physical traits and ancestry from DNA has limitations and requires ethical consideration.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.

The study found that in Latin America, ancestry varies by location, influences physical traits, and affects how people perceive their own heritage.

Fat tissue-derived cells show promise for repairing body tissues, but more research and regulation are needed for safe use.

The research found that different types of fibroblasts are involved in wound healing and that some blood cells can turn into fat cells during this process.

Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.

Noggin is necessary to start the hair growth phase in skin after birth.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Ruxolitinib effectively regrows hair in most patients with severe hair loss.