January 2009 in “Side effects of drugs annual” Some drugs can cause serious side effects like heart issues and nervous system problems, but certain drugs for Parkinson's and overactive bladder may be safer, though they still have some common side effects.
119 citations,
June 2005 in “Journal of Molecular and Cellular Cardiology” Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.
81 citations,
December 2009 in “Journal of Dermatological Science” Fat tissue stem cells may help increase hair growth.
34 citations,
January 1989 in “Toxicologic Pathology” A study found that minoxidil can damage the hearts of dogs and pigs, cautioning its use in humans.
27 citations,
August 1984 in “Experimental and Molecular Pathology” Stopping finasteride and closing PFO can help prevent strokes in young adults.
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March 2004 in “Annals of oncology” Pegylated liposomal doxorubicin is as effective as conventional doxorubicin but causes fewer heart problems and side effects.
271 citations,
May 2019 in “Cells” The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.
182 citations,
November 2017 in “Molecular Aspects of Medicine” The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.
144 citations,
August 2019 in “Cells” The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.
144 citations,
March 2013 in “Circulation Research” K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.
115 citations,
October 2009 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” The research found that Atypical Progeroid Syndrome has unique symptoms and is not caused by the buildup of a certain mutant protein.
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July 2010 in “Tissue Engineering Part A” Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.
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November 2017 in “Journal of Cellular Physiology” The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.
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May 2011 in “Liver transplantation” Liver transplantation is a viable option for children with propionic acidemia, improving quality of life and diet, but does not remove all risks and long-term brain outcomes are uncertain.
60 citations,
January 1989 in “Toxicologic Pathology” Using minoxidil on dogs can cause serious cardiovascular damage, including arterial injury and hemorrhagic lesions.
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February 2018 in “Journal of basic and clinical physiology and pharmacology/Journal of basic & clinical physiology & pharmacology” *Acorus calamus* has many medicinal benefits but needs more safety research.
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July 1995 in “Toxicologic Pathology” Minoxidil can harm dog's heart.
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January 2011 in “Elsevier eBooks” Systemic Lupus Erythematosus has varied symptoms and is hard to diagnose, affecting many body parts and requiring careful clinical judgment.
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January 2016 in “Vitamins and hormones” Thymosin β4 helps improve skin healing and reduce scarring.
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January 2013 in “BMJ Open” Severe baldness on the top of the head is linked to a higher chance of heart disease, especially in men under 60.
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June 2017 in “Molecular and Cellular Endocrinology” Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.
25 citations,
February 2017 in “Anticancer Research/Anticancer research” Ozone therapy might improve cancer treatment and reduce its side effects.
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October 2017 in “Biomolecules” Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.
24 citations,
May 2016 in “Stem Cell Reviews and Reports” The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.
19 citations,
January 2018 in “Acta dermato-venereologica” People with alopecia areata have higher levels of a heart disease marker than those without hair loss.
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April 2013 in “PLOS ONE” Mice with autoimmune hair loss showed signs of heart problems.