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Hair and nail cells share similar proteins, indicating a common differentiation pathway.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

β-catenin in the dermal papilla is crucial for normal hair growth and repair.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

The document provides a method to classify human hair growth stages using a model with human scalp on mice, aiming to standardize hair research.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Telocytes might help with skin repair and regeneration.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Laser hair removal effectiveness depends on targeting hair structures without harming the skin, and improvements require more research and expert collaboration.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Understanding hair follicle anatomy helps diagnose hair disorders.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Manipulating the catagen and telogen phases of hair growth could lead to treatments for hair disorders.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

The document concludes that hair is complex, with a detailed growth cycle, structure, and clinical importance, affecting various scientific and medical fields.

Chemotherapy often causes temporary hair loss, which is distressing and needs better treatment and support.

The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.

Laminin-511 is crucial for early hair growth and maintaining important hair development signals.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

EGF makes hair follicles grow longer but stops hair production.

All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.

Wool follicles are complex, involving interactions between different cell types and structures.