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Sorafenib is effective in treating Desmoid Tumor/Deep Fibromatosis.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Certain cells from hair follicles can create new hair and contribute to hair growth when implanted in mice.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.

Some medicinal plants can help heal wounds and may lead to new treatments.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.

The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.

Hair follicles may soon be used more for targeted and systemic drug delivery.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Platelet-rich plasma might help with hair growth and skin conditions, but more research is needed to prove its effectiveness and safety.

Women with PCOS and higher androgen levels are more likely to have fatty liver disease.

The paper concludes that the 1982 criteria for diagnosing systemic lupus erythematosus need updating to improve accuracy and involve dermatologists in the process.

ICG-enhanced NIR laser therapy may be a promising acne treatment with improvement and no side effects.

Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.

Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.

Improving skin barrier and using antifungal treatments can help manage dandruff.

Minoxidil and finasteride effectively treat hair loss.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

Human skin cells produce proenkephalin, which changes with environmental factors and skin diseases.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.