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Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Telogen effluvium is a reversible hair loss condition that requires a detailed diagnosis and often resolves on its own.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

Different types of skin cells play specific roles in development, healing, and cancer.

Androgens can both increase and decrease hair growth in different parts of the body.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

CDP is crucial for lung and hair follicle cell development.

Stem cell niches support, regulate, and coordinate stem cell functions.

The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Aging causes skin stem cells to work less effectively.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.