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Some skin diseases and their treatments can negatively affect male fertility.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

Fat-derived stem cells show promise for treating skin issues and improving wound healing, but more research is needed to confirm the best way to use them.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

More research is needed to understand how testosterone is maintained in adult males.

The levonorgestrel implant increases free testosterone and lowers SHBG more than DMPA-IM and the copper IUD.

Hormone therapy may increase migraines in transgender women and decrease them in transgender men; more research is needed on migraine management in transgender individuals.

Hormonal therapy changes skin and hair in transgender patients, who need better researched dermatologic care.

New treatments for relapsing multiple sclerosis are more effective and convenient but have higher risks of serious side effects.

New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.

Finasteride may cause long-lasting sexual side effects.

Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

Gender-affirming hormone treatments need better patient-focused outcome measurements and standardized data collection.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.

Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.

Testosterone therapy is beneficial for women's health and does not cause masculinization or liver damage, and it protects the heart and breasts.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.

Testosterone therapy seems safe for short-term use in postmenopausal women with low sexual desire, but more research on long-term effects is needed.

Surgery to lower high testosterone in postmenopausal women with certain ovarian tumors doesn't significantly affect their metabolism.

Most adrenal cortex tumors are benign and non-secreting, but proper diagnosis and treatment are important due to the rare possibility of cancer.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

A young woman with a rare hair loss condition improved with steroid and biotin treatment.

Effective treatments for severe alopecia areata are still lacking.

Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.

Mesotherapy might be a useful addition to dental surgery to reduce drug use and side effects, but more research is needed.

Nonsteroid treatments for alopecia areata show promise but need more high-quality research.