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    Glossary Intermediate Filaments

    structural proteins in cells providing mechanical support and stability

    Intermediate filaments are a type of structural protein found within cells that help maintain their shape and integrity. They are part of the cytoskeleton, which also includes microtubules and actin filaments, and they provide mechanical support to cells, enabling them to withstand stress and strain.

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    1. Types I and II Keratin Intermediate Filaments Cold Spring Harbor Perspectives in Biology · 2018 · 211 citations
    2. Trichohyalin, an intermediate filament-associated protein of the hair follicle. 1986 · 116 citations
    3. In Vitro Assembly and Structure of Trichocyte Keratin Intermediate Filaments 2000 · 91 citations
    4. The Intermediate Filament Architecture as Determined by X-Ray Diffraction Modeling of Hard α-Keratin Biophysical Journal · 2004 · 66 citations
    5. Cortical cell types and intermediate filament arrangements correlate with fiber curvature in Japanese human hair Journal of structural biology · 2008 · 62 citations
    6. Existence of trichohyalin-keratohyalin hybrid granules: Co-localization of two major intermediate filament-associated proteins in non-follicular epithelia Differentiation · 1994 · 54 citations
    7. Intermediate filaments: regulation of gene expression and assembly European journal of biochemistry · 1993 · 50 citations
    8. The role of disulfide bond formation in the structural transition observed in the intermediate filaments of developing hair Journal of Structural Biology · 2012 · 39 citations
    9. Structural changes in the trichocyte intermediate filaments accompanying the transition from the reduced to the oxidized form Journal of Structural Biology · 2007 · 31 citations
    10. Regulation of hard α-keratin mechanics via control of intermediate filament hydration: matrix squeeze revisited Proceedings of the Royal Society B Biological Sciences · 2012 · 30 citations
    11. Isolation of intermediate filament assemblies from human hair follicles. The Journal of Cell Biology · 1985 · 28 citations
    12. The Autoimmune Regulator (AIRE), Which Is Defective in Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy Patients, Is Expressed in Human Epidermal and Follicular Keratinocytes and Associates With the Intermediate Filament Protein Cytokeratin 17 ˜The œAmerican journal of pathology · 2011 · 24 citations
    13. In vivo formation steps of the hard α-keratin intermediate filament along a hair follicle: Evidence for structural polymorphism Journal of Structural Biology · 2006 · 22 citations
    14. Three-dimensional modelling of interchain sequence similarities and differences in the coiled-coil segments of keratin intermediate filament heterodimers highlight features important in assembly Journal of Structural Biology · 2007 · 13 citations
    15. Self-consistent field theory for the interactions between keratin intermediate filaments BMC Biophysics · 2013 · 12 citations
    16. From structural resilience to cell specification — Intermediate filaments as regulators of cell fate ˜The œFASEB journal · 2020 · 9 citations
    17. The Molecular Architecture for the Intermediate Filaments of Hard<i>α</i>-Keratin Based on the Superlattice Data Obtained from a Study of Mammals Using Synchrotron Fibre Diffraction Biochemistry Research International · 2011 · 7 citations
    18. A general mathematical model for the in vitro assembly dynamics of intermediate filament proteins Biophysical journal · 2022 · 5 citations
    19. Direct evidence supporting the existence of a helical dislocation in protofilament packing in the intermediate filaments of oxidized trichocyte keratin Journal of Structural Biology · 2018 · 3 citations
    20. The structure of human trichohyalin : potential multiple roles as a functional ef-hand-like calcium-binding protein, a cornified cell envelope precursor, and an intermediate filament-associated (cross-linking) protein 1993 · 2 citations
    21. Genes for intermediate filament proteins and the draft sequence of the human genome Journal of Cell Science · 2001 · 287 citations
    22. Cyclic hair-loss and regrowth in transgenic mice overexpressing an intermediate filament gene. The EMBO Journal · 1990 · 93 citations
    23. Hair follicle differentiation: expression, structure and evolutionary conservation of the hair type II keratin intermediate filament gene family Development · 1992 · 65 citations
    24. Regulation of a hair follicle keratin intermediate filament gene promoter Journal of Cell Science · 1998 · 39 citations
    25. Complete sequence of a hair-like intermediate filament type II keratin gene DNA sequence · 1993 · 15 citations
    26. Structure of intermediate filament assembly in hair deduced from hydration studies using small-angle neutron scattering Journal of structural biology · 2019 · 9 citations
    27. Carbon-13 n.m.r. studies of keratin intermediate filament of human hair Polymer · 1998 · 5 citations
    28. Disulfide Cross-Linked Network Structure of Intermediate Filament and Matrix in Hair and Wool Cortices Sen'i Gakkaishi · 2015 · 4 citations
    29. ‘Hard’ and ‘soft’ principles defining the structure, function and regulation of keratin intermediate filaments Current Opinion in Cell Biology · 2002 · 686 citations
    30. Cryo-Electron Microscopy of Trichocyte (Hard α-Keratin) Intermediate Filaments Reveals a Low-Density Core Journal of Structural Biology · 2002 · 48 citations