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960-990 / 1000+ resultsresearch Hair Keratins and Hair Follicle–Specific Epithelial Keratins
Hair and follicle keratins differ in structure and expression, especially in cysteine content.
research LB1609 The evolutionary trajectory of primate skin appendage traits
This study found that humans have a much higher eccrine gland density than chimpanzees and macaques, suggesting a unique evolutionary path for human skin features.
research Cutaneous Manifestations in Diabetes
This review explores and updates previous findings on the skin manifestations associated with diabetes, questioning some established signs while introducing additional cutaneous symptoms linked to the condition.
research Applications of Human Pluripotent Stem Cell–Derived Skin Organoids in Dermatology
This study provided an overview of skin organoids created from pluripotent stem cells, showcasing their potential in dermatologic research and future clinical applications, while noting challenges such as lengthy differentiation protocols that result in heterogeneous products.
research Three-dimensional analyses of touch domes in the hairy skin of the cat paw reveal morphological substrates for complex sensory processing
This study revealed the complex three-dimensional innervation of touch domes in cat forepaw skin, highlighting the extensive branching and unmyelinated endings associated with Merkel cell–axon complexes.
research Gender-linked differences in human skin
This review discusses gender-linked skin differences, such as hormone metabolism and sebum production, and reports no new findings; it suggests these insights might inform male-specific dermatological treatments or cosmetic products.
research Epidermis reconstructed from the outer root sheath of human hair follicle on de-epidermized dermis. Effect of retinoic acid
research Skin and glucocorticoids: effects of local skin glucocorticoid impairment on skin homeostasis
Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.
research Does dry skin indicate defective epidermal permeability barrier?
This study observed that skin dryness does not seem to indicate impaired epidermal barrier function, as there was no negative correlation between stratum corneum water content and transepidermal water loss.
research Novel approaches to characterize age‐related remodelling of the dermal‐epidermal junction in 2D, 3D and in vivo
This study used 3D imaging to reveal age-related reductions in the volumes and connectivity of dermal papillae and rete ridges at the dermal-epidermal junction, which are not fully apparent in 2D examinations.
research Structural and biochemical changes underlying a keratoderma-like phenotype in mice lacking suprabasal AP1 transcription factor function
This study found that inhibiting AP1 transcription factor activity in the suprabasal epidermis of mice alters keratinocyte gene expression, reducing barrier integrity and mimicking human keratoderma.
research 25 Years of Epidermal Stem Cell Research
Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.
research THE METROPOLITAN DERMATOLOGICAL SOCIETY OF LOS ANGELES
This report discusses a case of an intradermal nevus in a 42-year-old woman and provides no clinical findings beyond a biopsy showing hyperkeratosis and cellular pigmentary changes.
research Tactile sensitivity in the rat: a correlation between receptor structure and function
In this study, researchers found that the glabrous skin of the rat forelimb contains sparse Meissner corpuscles and Merkel complexes, with more slowly adapting afferents in the palm and rapidly adapting afferents in the digit extremity.
research Cutaneous Manifestations in Thyroid Disorders
This study found that specific and nonspecific skin changes can serve as important indicators for diagnosing thyroid diseases, even in patients who appear clinically normal.
research Reconstruction of Tissue Engineered Skin Substitute Containing Appendages Using Dermal Papillae Cells And Keratinocytes
This study found that incorporating dermal papillae cells and keratinocytes into dermal substitutes promoted better wound healing, reduced contraction, and enabled appendage formation in tissue-engineered skin on mice.
research Langerin+ Dendritic Cells in Cutaneous Fibrosis: The TGF-β1 Signaling Axis
This study synthesizes knowledge of how dendritic cell signals, epithelial integrins, and fibroblast activity converge on TGF-β1 to maintain or disrupt skin healing, contrasting normal and fibrotic scar formation and suggesting possible integrin and immune-targeted treatments for skin fibrosis.
research Epidermal stem cells in the skin
This article reviews the current understanding of epidermal stem cells and their role in skin and hair-follicle regeneration but presents no new research findings.
research Atrichia and Papular Lesions: Report of a Case
This case report details atrichia with papular lesions in a 4-year-old girl, highlighting specific histological findings on her scalp and other affected areas.
research Patterns of expression of trichocytic and epithelial cytokeratins in mammalian tissues. I. Human and bovine hair follicles
In this study, researchers observed that trichocytic and epithelial cytokeratins have distinct expression patterns within various human and bovine hair follicle cells, contributing to understanding hair follicle development and growth.
research Functional Genome and Proteome Analyses of Cutaneous Autoimmune Diseases
This review discusses current genomics and proteomics research on cutaneous autoimmune diseases, noting overlapping gene patterns but highlighting the scarcity of data on local gene expression in affected tissues.
research Endogenous human skin equivalent promotes in vitro morphogenesis of follicle-like structures
This study demonstrated that an engineered human skin equivalent can generate follicle-like structures resembling fetal skin, highlighting the role of the dermal compartment in directing epithelial cell fate in vitro.
research Glossary
This abstract provides a glossary of medical terms related to skin, joints, and other conditions, without reporting new research findings.
research Apoptosis in Hair and Skin: A Review
This review discusses how targeting apoptosis pathways in hair and skin cells can inform the development of novel therapies, but it reports no clinical findings.
research “Degeneration” in Dermatopathology
This article aims to enumerate and describe the types of tissue degeneration observed in various dermatopathological conditions, offering beneficial insights for residents studying the deterioration of skin tissues due to inflammatory, infective, drug-induced, or neoplastic stimuli.
research Skin Diseases (Noncancerous)
This article reviews the most common skin diseases worldwide and reports no new clinical findings.
research Organization and expression of hair follicle genes
research The Scalp Involvements in the Connective Tissue Diseases
This study reported that connective tissue diseases frequently lead to severe scalp and hair issues, including a risk of permanent cicatricial alopecia, particularly among young women.
research Pinkus' Guide to Dermatohistopathology
This abstract outlines dermatological topics related to skin pathology and does not provide any new research findings.