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SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.

The study found that sweat glands normally suppress immune responses, but this is disrupted in certain skin diseases, possibly contributing to their development.

People with Down syndrome have higher rates of certain immune-related conditions and need special medical attention.

The new skin-targeted COVID-19 vaccine creates strong immune responses and could improve vaccination methods.

People with autoimmune skin diseases often have hearing problems and should get their hearing checked early.

Jagged-1 in skin Tregs is crucial for timely wound healing by recruiting specific immune cells.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Tiny natural vesicles from cells might help treat hair loss.

Certain drugs increase calcium levels in cancer cells by triggering internal calcium release.

The S250C variant in a gene may cause autoimmunity and immunodeficiency by impairing protein function.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Accurate diagnosis is key for treating different kinds of hair loss, and immune response variations may affect the condition and treatment results.

New protein changes may be involved in the immune attack on hair follicles in alopecia areata.

Hair graying is influenced by factors like nerves, fat cells, and immune cells, not just hair follicles.

Retinol may affect immune responses in people with frequent skin boils.

Alopecia areata is likely caused by a combination of genetic factors and immune system dysfunction, and may represent different diseases with various causes.

Special immune cells called Tregs can help prevent lung scarring by blocking a specific growth factor.

Hair regrowth was seen in 83% of children with alopecia, immune system plays a role in the condition, and various treatments showed effectiveness for hair and nail disorders.

New drugs targeting DNA enzymes show promise for cancer treatment but have side effects like immune system suppression and hair loss.

Fetal skin has unique immune cells different from adult skin.

Stress can worsen skin conditions by affecting hormone levels and immune response.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

Some cancer and immune system drugs can cause serious side effects, including heart, lung, nerve, and organ damage, which need careful monitoring and management.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

ADM scaffolds help skin heal by promoting a healing-type immune response.

The conditions alopecia areata, primary sclerosing cholangitis, and ulcerative colitis may be linked by shared autoimmune and cell death mechanisms.

New treatments for hair loss are showing promise due to better understanding of genetics and the immune system.

Two young cats with a severe ear and skin condition improved with immune system-targeting treatments.