This study suggests that incorporating exogenous melatonin in the treatment of certain skin disorders, like psoriasis and eczema, can improve treatment efficiency, normalize immune parameters, and reduce disease relapses.
November 2020 in “Journal of the American Academy of Dermatology” Intense pulsed light with radiofrequency showed mixed results in improving quality of life for hidradenitis suppurativa patients, with no clinical improvements.
July 2004 in “Journal of the American Academy of Dermatology”
21 citations
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August 2013 in “Journal of Dermatological Treatment” This review discusses the mixed evidence and high risk of bias in studies on low-level light therapy for treating androgenetic alopecia and calls for rigorous randomized controlled trials to assess its efficacy.
January 1981 in “Elsevier eBooks”
6 citations
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September 2018 in “Journal of Dermatological Treatment” This review examines the FDA's 510(k) approval process for low-level laser therapy devices used in treating androgenetic alopecia and reports no new clinical findings.
November 2022 in “Journal of Investigative Dermatology” This study found that using a home-use LED mask with specific wavelengths improved signs of skin aging in both ex-vivo and clinical settings.
March 2005 in “Journal of The American Academy of Dermatology” The two lotions used day and night may be a good alternative to minoxidil for hair loss treatment with better cosmetic effects and tolerance.
July 2022 in “Journal of Investigative Dermatology”
28 citations
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January 2003 in “Skin pharmacology and physiology” This study found that melatonin's effect on HaCaT keratinocyte proliferation varied with concentration and incubation time, with no cytotoxic effects observed at suitable concentrations for skin treatment.
November 2024 in “Dermatology Online Journal” This review found promising evidence for the efficacy of certain laser and light-based therapies in treating various forms of alopecia, such as low-level light therapy for androgenetic alopecia and excimer laser for alopecia areata, but emphasized the need for further understanding of these treatments.
This article reviews low-level light therapy for various types of hair loss and reports no new clinical results; the authors note its safety and advantages but lack data on individual treatment response.
This study found that home use of low-level light therapy reduced inflammation and symptoms like itching and burning in women with frontal fibrosing alopecia over six months.
July 2006 in “Hair transplant forum international” This abstract mentions the XI International Congress of the ISHR in Bari but reports no new research findings.
April 2012 in “Informa Healthcare eBooks” Telogen effluvium is a condition that causes temporary hair loss.
8 citations
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July 2020 in “Medicine” In this study, low-level light therapy using a new helmet-type device significantly increased hair density and thickness in patients with androgenetic alopecia, showing no adverse events or side effects, suggesting it may be a safe and effective treatment option for both sexes.
April 2023 in “Journal of Investigative Dermatology” The study identified increased IL-24 expression in keratinocytes and fibroblasts exposed to particulate matter, contributing to skin aging by promoting conditions similar to age-related changes such as increased MMP1 expression and decreased type I collagen production.
1 citations
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June 2022 in “Photobiomodulation, photomedicine, and laser surgery” This literature watch compiles recent studies on photobiomodulation therapy across various applications, offering no new empirical findings.
December 2023 in “Trials” In this randomized controlled trial involving breast cancer patients undergoing chemotherapy, this study investigated the efficacy of low-level light therapy for preventing hair loss, measuring outcomes like hair count and patient quality of life, but the abstract does not report specific results.
195 citations
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January 2008 in “Photochemistry and Photobiology” This review discusses the effects of visible light on human skin, highlighting its role in pigmentation, thermal damage, and the treatment of several skin conditions, while noting limited sunscreen protection against it; no new clinical results are reported.
January 2026 in “Forum Dermatologicum” This review concluded that LED-based photobiomodulation is generally safe and effective for certain dermatologic conditions, though consumer devices often show less efficacy compared to professional systems.
In scalded rats, this study found that early melatonin administration may reduce oxidative stress and inflammation, thus protecting hair follicle cells after severe burns.
March 2017 in “Jurnal materi dan pembelajaran fisika” This review discusses applications of light diffraction in healthcare, highlighting its use in LASIK procedures, optogenetics, and measuring hair diameter, but reports no new results.
December 2023 in “Palestinian medical and pharmaceutical journal/Palestinian medical & pharmaceutical journal” The pilot study found that while women with habitual short sleep increased their sleep duration by an average of 40.7 minutes, there were no significant changes in insulin sensitivity, androgens, or leptin levels post-intervention, suggesting further research is needed.
4 citations
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February 2014 in “Proceedings of SPIE” This review discusses the diverse applications of low-level laser therapy in aesthetic dermatology, especially for managing alopecia, but notes that comprehensive literature on its effectiveness is lacking.
15 citations
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June 2023 in “Journal of Microbiology and Biotechnology” In this study, researchers found that an ethyl acetate extract of the green microalga Scenedesmus deserticola significantly increased the viability of human dermal fibroblasts by over 20% compared to a control and identified a potent anti-UV compound, loliolide, through further fractionation.
April 2023 in “Journal of Investigative Dermatology” This study found that the oral IRAK4-inhibitors BAY 1834845 and BAY 1830839 reduced skin inflammation and systemic inflammatory responses in healthy volunteers, showing similar pharmacodynamic effects to prednisolone when challenged with topical imiquimod and intravenous LPS.
31 citations
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June 2018 in “Dermatologic Surgery” In this randomized, double-blind trial, researchers observed that low-level laser therapy led to significantly greater hair regrowth on treated areas compared to a sham treatment in patients with androgenetic alopecia over 24 weeks, suggesting it as a potentially effective and safe option.
January 2000 in “Optics Letters” This study found that the maximum infrared temperature of laser-irradiated hair depends on melanin type, with eumelanin-rich hair reaching higher temperatures than pheomelanin-containing hair.
17 citations
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December 2015 in “International Journal of Cosmetic Science” This review discusses the effectiveness of non-thermal, non-ablative devices like light-emitting diodes in treating various skin and hair conditions but reports no new clinical findings.