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The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Telogen effluvium is a reversible hair loss condition that requires a detailed diagnosis and often resolves on its own.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Iron deficiency may be related to hair loss, but there's not enough evidence to recommend iron screening or supplements for all hair loss patients.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

Targeted cancer therapies often cause serious skin problems that need careful management.

Some herbal therapies may help with skin conditions, but more research is needed to confirm their safety and effectiveness.

Special fiber materials boost the healing properties of certain stem cells.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.

High androgen levels in young women with PCOS are linked to higher blood pressure.

CDP is crucial for lung and hair follicle cell development.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

Stress-related substance P may lead to hair loss and negatively affect hair growth.

Some people with pattern hair loss may also have scalp inflammation and scarring similar to lichen planopilaris.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

Generalized pustular psoriasis patients often need strong medication and careful treatment due to flare-ups and complications.

Androgens, like testosterone, are crucial for early testicular descent in rats.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Some vitamins and minerals like vitamin D and iron can help with certain types of hair loss, but more research is needed for others.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.